PHT-427

CCCCCCCCCCCCC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2

InChIKey=BYWWNRBKPCPJMG-UHFFFAOYSA-N

InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
RAC-beta serine/threonine-protein kinase 1 Target ID: P31751 Gene ID: 208.0 Gene Symbol: AKT2 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/20197390	Inhibitor 8504		2.67 µM [Ki]
3-phosphoinositide-dependent protein kinase 1 4 Target ID: O15530 Gene ID: 5170.0 Gene Symbol: PDPK1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/20197390	Inhibitor 8504		5.2 µM [Ki]

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:31:48 GMT 2025` Edited by `admin` on `Mon Mar 31 21:31:48 GMT 2025`
Record UNII	543K8ZN6LH
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

PHT427

Preferred Name

English

PHT-427

Code

English

4-DODECYL-N-1,3,4-THIADIAZOL-2-YLBENZENESULFONAMIDE

Systematic Name

English

BENZENESULFONAMIDE, 4-DODECYL-N-1,3,4-THIADIAZOL-2-YL-

Systematic Name

English

Code System Code Type Description

FDA UNII

543K8ZN6LH