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Details

Stereochemistry ACHIRAL
Molecular Formula C36H37N7O4
Molecular Weight 631.7235
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of MGB-BP-3

SMILES

CN1C=C(NC(=O)C2=CC(NC(=O)C3=CC=C(\C=C\C4=CC5=C(C=CC=C5)N=C4)C=C3)=CN2C)C=C1C(=O)NCCN6CCOCC6

InChI

InChIKey=OEKXCVYZBVOWBR-BQYQJAHWSA-N
InChI=1S/C36H37N7O4/c1-41-24-30(20-32(41)35(45)37-13-14-43-15-17-47-18-16-43)40-36(46)33-21-29(23-42(33)2)39-34(44)27-11-9-25(10-12-27)7-8-26-19-28-5-3-4-6-31(28)38-22-26/h3-12,19-24H,13-18H2,1-2H3,(H,37,45)(H,39,44)(H,40,46)/b8-7+

HIDE SMILES / InChI

Molecular Formula C36H37N7O4
Molecular Weight 631.7235
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

MGB-BP 3 is an antibacterial agent being developed by MGB Biopharma. This drug is now in phase II clinical trial to assess the safety, tolerability, and efficacy of incremental doses in patients with Clostridium difficile-associated diarrhea. In addition, this drug is studied for the treatment of Gram-positive infections; and skin and soft tissue infections.

Approval Year

Sample Use Guides

Patients will be administered an oral dose of 125mg b.i.d. MGB-BP-3 for 10 days (Day 1 to Day 10).
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Dec 16 11:10:57 GMT 2023
Edited
by admin
on Sat Dec 16 11:10:57 GMT 2023
Record UNII
532PWU9738
Record Status Validated (UNII)
Record Version
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Name Type Language
MGB-BP-3
Code English
MGB-BP3
Common Name English
J2.725.402K
Code English
4-((4-(4-((E)-2-(3-QUINOLYL)VINYL)BENZOYLAMINO)-1-METHYL-1H-PYRROLE-2-YL)CARBONYLAMINO)-1-METHYL-N-(2-MORPHOLINOETHYL)-1H-PYRROLE-2-CARBOXAMIDE
Systematic Name English
1H-PYRROLE-2-CARBOXAMIDE, 1-METHYL-N-(1-METHYL-5-(((2-(4-MORPHOLINYL)ETHYL)AMINO)CARBONYL)-1H-PYRROL-3-YL)-4-((4-((1E)-2-(3-QUINOLINYL)ETHENYL)BENZOYL)AMINO)-
Systematic Name English
Code System Code Type Description
CAS
1000277-08-6
Created by admin on Sat Dec 16 11:10:57 GMT 2023 , Edited by admin on Sat Dec 16 11:10:57 GMT 2023
PRIMARY
PUBCHEM
23730143
Created by admin on Sat Dec 16 11:10:57 GMT 2023 , Edited by admin on Sat Dec 16 11:10:57 GMT 2023
PRIMARY
DRUG BANK
DB12892
Created by admin on Sat Dec 16 11:10:57 GMT 2023 , Edited by admin on Sat Dec 16 11:10:57 GMT 2023
PRIMARY
FDA UNII
532PWU9738
Created by admin on Sat Dec 16 11:10:57 GMT 2023 , Edited by admin on Sat Dec 16 11:10:57 GMT 2023
PRIMARY
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