U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2016
495
Substance Class Protein
Created
by admin
on Sat Dec 16 17:37:21 UTC 2023
Edited
by admin
on Sat Dec 16 17:37:21 UTC 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
52CMI0WC3Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ATEZOLIZUMAB
DASH   INN   USAN   WHO-DD  
INN   USAN  
Official Name English
ATEZOLIZUMAB [USAN]
Common Name English
TECENTRIQ
Common Name English
RG-7446
Code English
ATEZOLIZUMAB [JAN]
Common Name English
MPDL3280A
Code English
ATEZOLIZUMAB [MI]
Common Name English
atezolizumab [INN]
Common Name English
AN ANTIBODY TO PROGRAMMED DEATH LIGAND 1 FOR CANCER THERAPY
Common Name English
ATEZOLIZUMAB [PURPLE BOOK CDER]
Common Name English
0INE2SFD9E
Common Name English
RG7446
Code English
Atezolizumab [WHO-DD]
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN CD ANTIGEN CD274) (HUMAN MONOCLONAL MPDL3280A HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL MPDL3280A .KAPPA.-CHAIN, DIMER
Common Name English
MPDL-3280A
Code English
Classification Tree Code System Code
WHO-ATC L01XC32
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
FDA ORPHAN DRUG 574817
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
FDA ORPHAN DRUG 619317
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
FDA ORPHAN DRUG 792320
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
FDA ORPHAN DRUG 769320
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
FDA ORPHAN DRUG 541216
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
FDA ORPHAN DRUG 550616
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
NDF-RT N0000191260
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
NCI_THESAURUS C128057
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
Code System Code Type Description
ChEMBL
CHEMBL3707227
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY
LACTMED
Atezolizumab
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY
DRUG BANK
DB11595
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY
WIKIPEDIA
Atezolizumab
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY
SMS_ID
100000163921
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY
NCI_THESAURUS
C106250
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY
EVMPD
SUB178312
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY
NDF-RT
N0000011175
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY Antibodies [Chemical/Ingredient]
NDF-RT
N0000183512
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY Antibodies, Monoclonal, Humanized [Chemical/Ingredient]
DAILYMED
52CMI0WC3Y
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY
INN
9814
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY
FDA UNII
52CMI0WC3Y
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY
CAS
1380723-44-3
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY
USAN
CD-146
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY
RXCUI
1792776
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY
DRUG CENTRAL
5151
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY
CAS
1422185-06-5
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
NO STRUCTURE GIVEN
MERCK INDEX
m11954
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY
NDF-RT
N0000191259
Created by admin on Sat Dec 16 17:37:21 UTC 2023 , Edited by admin on Sat Dec 16 17:37:21 UTC 2023
PRIMARY Programmed Death Receptor-1-directed Antibody Interactions [MoA]
From To
1_22 1_96
1_145 1_201
1_262 1_322
1_368 1_426
2_22 2_96
2_145 2_201
2_262 2_322
2_368 2_426
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_221 3_214
2_221 4_214
1_227 2_227
1_230 2_230
Related Record Type Details
PROGRAMMED CELL DEATH 1 LIGAND 1
TARGET -> INHIBITOR
BINDING
Related Record Type Details
ATEZOLIZUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Volume of Distribution PHARMACOKINETIC
Molecular Formula CHEMICAL
Biological Half-life PHARMACOKINETIC
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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DISCLAIMER
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