ALICONAZOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C18H13Cl3N2
Molecular Weight	363.668
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClC1=CC=C(C=C1)C(\CN2C=CN=C2)=C\C3=C(Cl)C=C(Cl)C=C3

InChI

InChIKey=WNGFKUOERJDDIY-OQLLNIDSSA-N

InChI=1S/C18H13Cl3N2/c19-16-4-1-13(2-5-16)15(11-23-8-7-22-12-23)9-14-3-6-17(20)10-18(14)21/h1-10,12H,11H2/b15-9+

HIDE SMILES / InChI

Molecular Formula	C18H13Cl3N2
Molecular Weight	363.668
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3069196

Aliconazole is an antifungal imidazole derivative, developed by Knoll Pharmaceuticals. Aliconazole was previously in phase III clinical trials for the determination of efficacy in the topical treatment of cutaneous fungal infections. The proposed use includes superficial fungal infections, including dermatomycoses, tinea versicolor, and cutaneous and vaginal candidiasis

Originator

Approval Year

PubMed

Title	Date	PubMed
Overview of medically important antifungal azole derivatives.	1988 Apr	3069196

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:18:31 GMT 2023` Edited by `admin` on `Fri Dec 15 16:18:31 GMT 2023`
Record UNII	51HX72H34H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ALICONAZOLE

Official Name

English

aliconazole [INN]

Common Name

English

(Z)-1-(2,4-DICHLORO-.BETA.-(P-CHLOROPHENYL)CINNAMYL)IMIDAZOLE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C514