PRODIPINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H25N
Molecular Weight	279.4192
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)N1CCC(CC1)(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=CFOOTBBXHJHHMT-UHFFFAOYSA-N

InChI=1S/C20H25N/c1-17(2)21-15-13-20(14-16-21,18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,17H,13-16H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C20H25N
Molecular Weight	279.4192
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7222702 | https://www.ncbi.nlm.nih.gov/pubmed/7191294 | https://www.ncbi.nlm.nih.gov/pubmed/347467 |

Prodipine (also known as BY-101) is diphenylpiperidines derivative patented by Chemische Fabrik Promonta G.m.b.H. as an anti parkinsonian agent. Prodipine showed monoamine oxidase inhibiting effects in vitro (liver and brain homogenates) similar to those of harmaline. In preclinical studies, Prodipine caused no tachyphylaxis, no increased salivation, or hyperthermia, and had lower toxicity in mice than amphetamine or pemoline. Prodipine decreased reserpine-induced ptosis, antagonized tremorine-induced seizures, and caused only mild hypertension in mice.

Originator

Approval Year

PubMed

Title	Date	PubMed
CSF-changes of HVA and 5-HIAA during intermittent and continuous Parkinson therapy with particular regard to prodipin application.	1978-03	347467

Patents

Sample Use Guides

In Vivo Use Guide

20 mg

Route of Administration: Intravenous

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:27:56 GMT 2025` Edited by `admin` on `Mon Mar 31 18:27:56 GMT 2025`
Record UNII	51567MYG7V
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PRODIPINE

Official Name

English

PRODIPINE [MI]

Preferred Name

English

prodipine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C38149