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Details

Stereochemistry ACHIRAL
Molecular Formula C20H25N
Molecular Weight 279.4192
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PRODIPINE

SMILES

CC(C)N1CCC(CC1)(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=CFOOTBBXHJHHMT-UHFFFAOYSA-N
InChI=1S/C20H25N/c1-17(2)21-15-13-20(14-16-21,18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-12,17H,13-16H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C20H25N
Molecular Weight 279.4192
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Prodipine (also known as BY-101) is diphenylpiperidines derivative patented by Chemische Fabrik Promonta G.m.b.H. as an anti parkinsonian agent. Prodipine showed monoamine oxidase inhibiting effects in vitro (liver and brain homogenates) similar to those of harmaline. In preclinical studies, Prodipine caused no tachyphylaxis, no increased salivation, or hyperthermia, and had lower toxicity in mice than amphetamine or pemoline. Prodipine decreased reserpine-induced ptosis, antagonized tremorine-induced seizures, and caused only mild hypertension in mice.

Originator

Approval Year

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
20 mg
Route of Administration: Intravenous
Substance Class Chemical
Record UNII
51567MYG7V
Record Status Validated (UNII)
Record Version