CP-376395

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H30N2O
Molecular Weight	326.4757
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC(CC)NC1=C(C)C(OC2=C(C)C=C(C)C=C2C)=NC(C)=C1

InChI

InChIKey=VIZBSVDBNLAVAW-UHFFFAOYSA-N

InChI=1S/C21H30N2O/c1-8-18(9-2)23-19-12-16(6)22-21(17(19)7)24-20-14(4)10-13(3)11-15(20)5/h10-12,18H,8-9H2,1-7H3,(H,22,23)

HIDE SMILES / InChI

Molecular Formula	C21H30N2O
Molecular Weight	326.4757
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Corticotropin releasing factor receptor 1 8 Target ID: CHEMBL1800 Sources: https://www.ncbi.nlm.nih.gov/pubmed/18288792	Inhibitor 8297		12.0 nM [Ki]

PubMed

Title	Date	PubMed
2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists.	2008 Mar 13	18288792
A comparison of ligand based virtual screening methods and application to corticotropin releasing factor 1 receptor.	2009 Jun-Jul	19230731
Elevated corticosterone in the amygdala leads to persistent increases in anxiety-like behavior and pain sensitivity.	2010 Dec 25	20573588

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 09:23:17 GMT 2023` Edited by `admin` on `Sat Dec 16 09:23:17 GMT 2023`
Record UNII	5113G7FP34
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CP-376395

Common Name

English

4-PYRIDINAMINE, N-(1-ETHYLPROPYL)-3,6-DIMETHYL-2-(2,4,6-TRIMETHYLPHENOXY)-

Systematic Name

English

Code System Code Type Description

FDA UNII

5113G7FP34

Created by admin on Sat Dec 16 09:23:17 GMT 2023 , Edited by admin on Sat Dec 16 09:23:17 GMT 2023

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EPA CompTox

DTXSID0047298

Created by admin on Sat Dec 16 09:23:17 GMT 2023 , Edited by admin on Sat Dec 16 09:23:17 GMT 2023

PRIMARY

PUBCHEM

9862166

Created by admin on Sat Dec 16 09:23:17 GMT 2023 , Edited by admin on Sat Dec 16 09:23:17 GMT 2023

PRIMARY

CAS

175140-00-8

Created by admin on Sat Dec 16 09:23:17 GMT 2023 , Edited by admin on Sat Dec 16 09:23:17 GMT 2023

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Related Record Type Details


					5113G7FP34

CP-376395

ACTIVE MOIETY