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Details

Stereochemistry ACHIRAL
Molecular Formula C20H24Cl2N10
Molecular Weight 475.378
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PICLOXYDINE

SMILES

ClC1=CC=C(NC(=N)NC(=N)N2CCN(CC2)C(=N)NC(=N)NC3=CC=C(Cl)C=C3)C=C1

InChI

InChIKey=YNCLPFSAZFGQCD-UHFFFAOYSA-N
InChI=1S/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30)

HIDE SMILES / InChI

Molecular Formula C20H24Cl2N10
Molecular Weight 475.378
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Picloxydine is a heterocyclic biguanide with antibacterial and antiplaque activity. 0.4% Picloxydine produces a highly significant drop in the number of aerobic organisms. 0.4% Picloxydine is far more effective than 0.2% Picloxydine or chlorhexidine in reducing the total viable count of oral aerobic and anaerobic organisms. It is used to treat superficial eye infections. Picloxydine is also used in eye drops in the topical therapy of trachoma. This drug can cause side effects - local intolerance reactions (temporary irritation, allergic reactions).

Approval Year

Sample Use Guides

In Vivo Use Guide
1 drop, 2-6 times per day
Route of Administration: Topical
Substance Class Chemical
Record UNII
4YC2PY3AEU
Record Status Validated (UNII)
Record Version