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Details

Stereochemistry ABSOLUTE
Molecular Formula C24H38O5
Molecular Weight 406.5555
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of ALFAPROSTOL

SMILES

COC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1C#C[C@@H](O)CCC2CCCCC2

InChI

InChIKey=OZDSQCVLNUIYLN-JNAAKWLTSA-N
InChI=1S/C24H38O5/c1-29-24(28)12-8-3-2-7-11-20-21(23(27)17-22(20)26)16-15-19(25)14-13-18-9-5-4-6-10-18/h2,7,18-23,25-27H,3-6,8-14,17H2,1H3/b7-2-/t19-,20+,21+,22-,23+/m0/s1

HIDE SMILES / InChI

Molecular Formula C24H38O5
Molecular Weight 406.5555
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 5 / 5
E/Z Centers 1
Optical Activity UNSPECIFIED

Description

Alfaprostol is a synthetic analogue of prostaglandin F2α. Its activity is similar to that of the endogenous PFG2α, causing luteolysis. Alfaprostol is recommended for use in the cow, sow and mare.

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
ALFABEDYL

PubMed

Sample Use Guides

In Vivo Use Guide
Alfaprostol is given as an intramuscular injection and the recommended dosage rate is : - 1.5 mg per 100 kg bodyweight cow; 2 mg per sow; 3 mg per mare
Route of Administration: Intramuscular
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
4XKL2JJ08I
Record Status Validated (UNII)
Record Version