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Description

Somatorelin is 29 amino acid analogue of human growth hormone-releasing hormone used as a diagnostic agent for determining growth hormone deficiency. Growth-hormone-releasing hormone (GHRH, somatoliberin) is the hypothalamic peptide hormone that specifically stimulates synthesis and release of growth hormone (GH, somatotropin) by somatotrope cells of the anterior pituitary gland. The hypothalamic hormone growth hormone (GH)-releasing hormone (GHRH) acts on specific GHRH receptors (GHRH-R) in the anterior pituitary gland to stimulate the synthesis and secretion of GH and to promote somatotrope expansion. Somatorelin is applied to determine the somatotropic function of the anterior pituitary gland in cases of suspected growth hormone deficiency. The test distinguishes between pituitary and hypothalamic disorders but is not suitable as a screening test for growth hormone deficiencies. Somatorelin has been used in trials studying the treatment of Aging, Elderly, Sleep Disorders, Hormone Deficiency, and Mild Cognitive Impairment.

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
Peripheral activities of growth hormone-releasing hormone.
2016 Jul

Sample Use Guides

In Vivo Use Guide
1μg/kg bodyweight
Route of Administration: Intravenous
Substance Class Protein
Created
by admin
on Sat Dec 16 02:03:58 UTC 2023
Edited
by admin
on Sat Dec 16 02:03:58 UTC 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
4UR7N9Z9MM
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SOMATORELIN
INN   MART.   WHO-DD  
INN  
Official Name English
SOMATOLIBERIN [MI]
Common Name English
SOMATORELIN [MART.]
Common Name English
GROWTH HORMONE RELEASING HORMONE, 1-44 HUMAN AMIDE
Common Name English
TYR-ALA-ASP-ALA-ILE-PHE-THR-ASN-SER-TYR-ARG-LYS-VAL-LEU-GLY-GLN-LEU-SER-ALA-ARG-LYS-LEU-LEU-GLN-ASP-ILE-MET-SER-ARG-GLN-GLN-GLY-GLU-SER-ASN-GLN-GLU-ARG-GLY-ALA-ARG-ALA-ARG-LEU-NH2
Common Name English
ESFARASE
Brand Name English
Somatorelin [WHO-DD]
Common Name English
GROWTH HORMONE-RELEASING FACTOR (HUMAN)
Common Name English
SOMATOLIBERIN
MI  
Common Name English
GHRH
Common Name English
GHRH(1-44)NH2
Common Name English
GHRF
Common Name English
somatorelin [INN]
Common Name English
GHRH(1-44) AMIDE
Common Name English
SOMATOLIBERIN, HUMAN
Common Name English
SOMATOCRININ
Common Name English
GRF 1-44
Common Name English
SOMATOLIBERIN (HUMAN)
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 785420
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
FDA ORPHAN DRUG 37389
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
FDA ORPHAN DRUG 36689
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
FDA ORPHAN DRUG 436814
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
WHO-VATC QV04CD05
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
WHO-ATC V04CD05
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
Code System Code Type Description
MERCK INDEX
m10110
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
PRIMARY Merck Index
EPA CompTox
DTXSID40232828
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
PRIMARY
DRUG BANK
DB12656
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
PRIMARY
ChEMBL
CHEMBL2108862
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
PRIMARY
CAS
83930-13-6
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
PRIMARY
SMS_ID
100000084046
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
PRIMARY
NCI_THESAURUS
C171035
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
PRIMARY
WIKIPEDIA
SOMATORELIN
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
PRIMARY
EVMPD
SUB10581MIG
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
PRIMARY
INN
6011
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
PRIMARY
CAS
9034-39-3
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
GENERIC (FAMILY)
FDA UNII
4UR7N9Z9MM
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
PRIMARY
RXCUI
236901
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
PRIMARY RxNorm
DRUG CENTRAL
4710
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
PRIMARY
PUBCHEM
16132353
Created by admin on Sat Dec 16 02:03:58 UTC 2023 , Edited by admin on Sat Dec 16 02:03:58 UTC 2023
PRIMARY
Related Record Type Details
SOMATORELIN ACETATE
SALT/SOLVATE -> PARENT
SOMATORELIN TRIFLUOROACETATE
SALT/SOLVATE -> PARENT
SOMATORELIN ACETATE
INGREDIENT -> STARTING MATERIAL
Related Record Type Details
SOMATORELIN
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:SEQUENCE(CALCULATED) CHEMICAL
NIH
NCATS
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