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Details

Stereochemistry ACHIRAL
Molecular Formula C5H9N3O10
Molecular Weight 271.1391
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PENTRINITROL

SMILES

OCC(CO[N+]([O-])=O)(CO[N+]([O-])=O)CO[N+]([O-])=O

InChI

InChIKey=BRBAEHHXGZRCBK-UHFFFAOYSA-N
InChI=1S/C5H9N3O10/c9-1-5(2-16-6(10)11,3-17-7(12)13)4-18-8(14)15/h9H,1-4H2

HIDE SMILES / InChI

Molecular Formula C5H9N3O10
Molecular Weight 271.1391
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Pentrinitrol is a metabolite of pentaerythritol tetranitrate. It has been introduced as an antianginal agent for man. Pentrinitrol decrease myocardial oxygen consumption and have a relatively long duration of action. The pharmacologic effects of pentrinitrol are similar to those of nitroglycerin. However, the duration of action of pentrinitrol is longer. Pentrinitrol produced lower pre-exercise systolic blood pressures and systolic blood pressures at point of angina. Pentrinitrol should permit patients to have fewer episodes of angina pectoris resulting from minor increases in physical activity. The same protection may also exist against angina pectoris produced by psychic stress. However, patients should still be cautioned against physical activity or psychic stress that ordinarily provokes angina pectoris.

Approval Year

PubMed

PubMed

TitleDatePubMed
[Therapy with NO donors-antiatherogenic and antioxidant actions].
2004 Feb
Patents

Sample Use Guides

In Vivo Use Guide
Single dose - 10 mg
Route of Administration: Other
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:05:21 UTC 2023
Edited
by admin
on Fri Dec 15 15:05:21 UTC 2023
Record UNII
4SL9HWA66P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PENTRINITROL
INN   MI   USAN   WHO-DD  
USAN   INN  
Official Name English
PETRIN
Brand Name English
PENTRINITROL [USAN]
Common Name English
Pentrinitrol [WHO-DD]
Common Name English
W 2197
Code English
PENTRINITROL [MI]
Common Name English
1,3-PROPANEDIOL, 2,2-BIS((NITROOXY)METHYL)-, MONONITRATE (ESTER)
Common Name English
Pentaerythritol trinitrate
Systematic Name English
W-2197
Code English
pentrinitrol [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29707
Created by admin on Fri Dec 15 15:05:21 UTC 2023 , Edited by admin on Fri Dec 15 15:05:21 UTC 2023
Code System Code Type Description
SMS_ID
100000082519
Created by admin on Fri Dec 15 15:05:21 UTC 2023 , Edited by admin on Fri Dec 15 15:05:21 UTC 2023
PRIMARY
NCI_THESAURUS
C91005
Created by admin on Fri Dec 15 15:05:21 UTC 2023 , Edited by admin on Fri Dec 15 15:05:21 UTC 2023
PRIMARY
CAS
1607-17-6
Created by admin on Fri Dec 15 15:05:21 UTC 2023 , Edited by admin on Fri Dec 15 15:05:21 UTC 2023
PRIMARY
ChEMBL
CHEMBL466660
Created by admin on Fri Dec 15 15:05:21 UTC 2023 , Edited by admin on Fri Dec 15 15:05:21 UTC 2023
PRIMARY
FDA UNII
4SL9HWA66P
Created by admin on Fri Dec 15 15:05:21 UTC 2023 , Edited by admin on Fri Dec 15 15:05:21 UTC 2023
PRIMARY
EPA CompTox
DTXSID10862712
Created by admin on Fri Dec 15 15:05:21 UTC 2023 , Edited by admin on Fri Dec 15 15:05:21 UTC 2023
PRIMARY
PUBCHEM
15353
Created by admin on Fri Dec 15 15:05:21 UTC 2023 , Edited by admin on Fri Dec 15 15:05:21 UTC 2023
PRIMARY
EVMPD
SUB09707MIG
Created by admin on Fri Dec 15 15:05:21 UTC 2023 , Edited by admin on Fri Dec 15 15:05:21 UTC 2023
PRIMARY
ECHA (EC/EINECS)
216-529-7
Created by admin on Fri Dec 15 15:05:21 UTC 2023 , Edited by admin on Fri Dec 15 15:05:21 UTC 2023
PRIMARY
MERCK INDEX
m8521
Created by admin on Fri Dec 15 15:05:21 UTC 2023 , Edited by admin on Fri Dec 15 15:05:21 UTC 2023
PRIMARY Merck Index
INN
3363
Created by admin on Fri Dec 15 15:05:21 UTC 2023 , Edited by admin on Fri Dec 15 15:05:21 UTC 2023
PRIMARY
MESH
C100210
Created by admin on Fri Dec 15 15:05:21 UTC 2023 , Edited by admin on Fri Dec 15 15:05:21 UTC 2023
PRIMARY
DRUG CENTRAL
3427
Created by admin on Fri Dec 15 15:05:21 UTC 2023 , Edited by admin on Fri Dec 15 15:05:21 UTC 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY