Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H14NO3 |
| Molecular Weight | 220.2445 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 1 |
SHOW SMILES / InChI
SMILES
COC1=C2OCOC2=CC3=C1C=[N+](C)CC3
InChI
InChIKey=KGZAOSLMBZSSTE-UHFFFAOYSA-N
InChI=1S/C12H14NO3/c1-13-4-3-8-5-10-12(16-7-15-10)11(14-2)9(8)6-13/h5-6H,3-4,7H2,1-2H3/q+1
| Molecular Formula | C12H14NO3 |
| Molecular Weight | 220.2445 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Cotarninium is a uterotonic agent. It increases the tone of smooth muscles of internal organs, particularly the uterus. Indicated for the treatment of uterus subinvolution (after childbirth and abortion), dysfunctional uterine bleeding and bleeding due to fibroids and inflammatory processes. Side effects are nausea, allergic reactions. Contraindications are pregnancy and hypersensitivity to the agent.
Approval Year
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Primary | STYPTICIN Approved UseIndicated for the treatment of delayed uterine involution, uterine bleeding after childbirth, abortion and others. Launch Date1964 |
|||
| Primary | STYPTICIN Approved UseIndicated for the treatment of delayed uterine involution, uterine bleeding after childbirth, abortion and others. Launch Date1964 |
PubMed
| Title | Date | PubMed |
|---|---|---|
| A new approach to alkaloid-like systems: synthesis and crystal structure of 1-(2-acetyl-11-meth-oxy-5,6-di-hydro-[1,3]dioxolo[4,5-g]pyrrolo-[2,1-a]isoquinolin-1-yl)propan-2-one. | 2017-11-01 |
|
| Metal-Free Activation of a C(sp)-H Bond of Aryl Acetylenes. | 2016-10-10 |
|
| Metabolic pathway profiling of the derivative of important herbal component noscapine. | 2016-02 |
|
| Validated stability-indicating TLC method for the determination of noscapine. | 2009-07 |
|
| Noscapine inhibits tumor growth with little toxicity to normal tissues or inhibition of immune responses. | 2000-07 |
|
| [The detection of abortion agents in biological material]. | 1992-01-01 |
Patents
| Substance Class |
Chemical
Created
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admin
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Edited
Mon Mar 31 22:57:51 GMT 2025
by
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Mon Mar 31 22:57:51 GMT 2025
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| Record UNII |
4SIM4898JC
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| Record Status |
Validated (UNII)
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20276-45-3
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160909
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4SIM4898JC
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admin on Mon Mar 31 22:57:51 GMT 2025 , Edited by admin on Mon Mar 31 22:57:51 GMT 2025
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