DARENZEPINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H21N3O2
Molecular Weight	347.4103
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1CCN(CC1)C(=O)\C=C2\C3=C(NC(=O)C4=C2C=CC=C4)C=CC=C3

InChI

InChIKey=VBQROPPRMFZXNC-NBVRZTHBSA-N

InChI=1S/C21H21N3O2/c1-23-10-12-24(13-11-23)20(25)14-18-15-6-2-3-8-17(15)21(26)22-19-9-5-4-7-16(18)19/h2-9,14H,10-13H2,1H3,(H,22,26)/b18-14+

HIDE SMILES / InChI

Molecular Formula	C21H21N3O2
Molecular Weight	347.4103
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://www.sciencedirect.com/science/article/pii/S0065774308610362 | https://www.ncbi.nlm.nih.gov/pubmed/11814816

Darenzepine is an antagonist of muscarinic receptors, developed by at Knoll/BASF Pharma. It is claimed to have antiulcer effect superior to pirenzepine and to have less anticholinergic adverse effects.

Approval Year

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:24:09 GMT 2025` Edited by `admin` on `Mon Mar 31 18:24:09 GMT 2025`
Record UNII	4SDY4L68FP
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DARENZEPINE

Official Name

English

(E)-1-((5,6-DIHYDRO-6-OXO-11-MORPHANTHRIDINYLIDENE)ACETYL)-4-METHYLPIPERAZINE

Preferred Name

English

darenzepine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29701