GUAMECYCLINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C29H38N8O8
Molecular Weight	626.6608
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12C[C@@]3([H])C(C(=O)C4=C(C=CC=C4O)[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(=O)NCN5CCN(CC5)C(=N)NC(N)=N)=C(O)[C@H]2N(C)C

InChI

InChIKey=DIRJDIBCAHCCFL-AQFAATAFSA-N

InChI=1S/C29H38N8O8/c1-28(44)13-5-4-6-16(38)17(13)21(39)18-14(28)11-15-20(35(2)3)22(40)19(24(42)29(15,45)23(18)41)25(43)33-12-36-7-9-37(10-8-36)27(32)34-26(30)31/h4-6,14-15,20,38,40-41,44-45H,7-12H2,1-3H3,(H,33,43)(H5,30,31,32,34)/t14-,15-,20-,28+,29-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C29H38N8O8
Molecular Weight	626.6608
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4565314 | https://www.ncbi.nlm.nih.gov/pubmed/5147865

Guamecycline, a tetracycline derivative was studied in patients with broncho-pulmonary diseases and for the treatment of acute pneumopathies. However, information about the current use of this compound is not available.

Approval Year

PubMed

Title	Date	PubMed
Guamecycline in bronchial infections due to Diplococcus pneumoniae.	1972 Jan-Feb	4156979

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Respiratory

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:21:22 GMT 2023` Edited by `admin` on `Sat Dec 16 16:21:22 GMT 2023`
Record UNII	4NQR4R6G3S
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GUAMECYCLINE

Official Name

English

Guamecycline [WHO-DD]

Common Name

English

GUAMECYCLINE [MI]

Common Name

English

guamecycline [INN]

Common Name

English

N-((4-(AMIDINOAMIDINO)-1-PIPERAZINYL)METHYL)-4-(DIMETHYLAMINO)-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-3,6,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-2-NAPHTHACENECARBOXAMIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1595