Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column. Indium In 111 pentetate ( 111In-DTPA) is indicated as an imaging agent in cisternography to study the flow of cerebrospinal fluid (CSF) in the brain, to diagnose abnormalities in CSF circulation, to assess and help localize the site of CSF leakage, and to test the patency of or localize blocks in CSF shunts.
Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Wed Apr 02 07:11:53 GMT 2025
by
admin
on
Wed Apr 02 07:11:53 GMT 2025
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| Protein Type | MONOCLONAL ANTIBODY CONJUGATE |
| Protein Sub Type | IGG1 |
| Sequence Origin | HUMANIZED MOUSE |
| Sequence Type | COMPLETE |
| Record UNII |
4L3VFU7249
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| Record Status |
Validated (UNII)
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| Record Version |
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Common Name | English | ||
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Preferred Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
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4L3VFU7249
Created by
admin on Wed Apr 02 07:11:53 GMT 2025 , Edited by admin on Wed Apr 02 07:11:53 GMT 2025
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C2217
Created by
admin on Wed Apr 02 07:11:53 GMT 2025 , Edited by admin on Wed Apr 02 07:11:53 GMT 2025
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| From | To |
|---|---|
| 1_22 | 1_96 |
| 1_143 | 1_199 |
| 1_219 | 3_219 |
| 1_225 | 2_225 |
| 1_228 | 2_228 |
| 1_260 | 1_320 |
| 1_366 | 1_424 |
| 2_22 | 2_96 |
| 2_143 | 2_199 |
| 2_219 | 4_219 |
| 2_260 | 2_320 |
| 2_366 | 2_424 |
| 3_23 | 3_94 |
| 3_139 | 3_199 |
| 4_23 | 4_94 |
| 4_139 | 4_199 |
| Related Record | Type | Details | ||
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TARGET->RADIOLIGAND |
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Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| MOIETY | RESIDUE_SPECIFIC | LYSINE | INDIUM CATION IN-111 | WJZ06C0H8L | ||
| FRAGMENT | RESIDUE_SPECIFIC | LYSINE | LYSINE-DOTA | KTZ0L57AI1 |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| Molecular Formula | CHEMICAL |
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| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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