INDIUM IN-111 EPRATUZUMAB TETRAXETAN

Description
Sources: https://www.drugbank.ca/drugs/DB09425 | https://www.drugs.com/mmx/indium-in-111-pentetate.html

Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column. Indium In 111 pentetate ( 111In-DTPA) is indicated as an imaging agent in cisternography to study the flow of cerebrospinal fluid (CSF) in the brain, to diagnose abnormalities in CSF circulation, to assess and help localize the site of CSF leakage, and to test the patency of or localize blocks in CSF shunts.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
hydrocephalus 8 Sources: http://www.nuclearonline.org/PI/Nycomed%20%20Indium%20DTPA%20In%20111.pdf	Diagnostic	Approved 8429	MPI INDIUM DTPA IN 111 Approved Use Unknown Launch Date 1982
syringomyelia 8 Sources: http://www.nuclearonline.org/PI/Nycomed%20%20Indium%20DTPA%20In%20111.pdf	Diagnostic	Approved 8429	MPI INDIUM DTPA IN 111 Approved Use Unknown Launch Date 1982
arachnoid cyst 8 Sources: http://www.nuclearonline.org/PI/Nycomed%20%20Indium%20DTPA%20In%20111.pdf	Diagnostic	Approved 8429	MPI INDIUM DTPA IN 111 Approved Use Unknown Launch Date 1982

Sample Use Guides

In Vivo Use Guide

The maximum recommended intrathecal dose in the average patient (70 kg) is 18.5 MBq, 500 μCi. The patient dose should be measured by a suitable radioactivity calibration system immediately prior to administration.

Route of Administration: Other

Substance Class	Protein Created by `admin` on `Sat Dec 16 16:07:44 GMT 2023` Edited by `admin` on `Sat Dec 16 16:07:44 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	4L3VFU7249
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

INDIUM IN-111 EPRATUZUMAB TETRAXETAN

Common Name

English

EPRATUZUMAB TETRAXETAN INDIUM IN-111

Common Name

English

INDIUM IN 111 LL2 IGG

Common Name

English

111IN-DOTA EPRATUZUMAB

Common Name

English

Code System Code Type Description

FDA UNII

4L3VFU7249

Created by admin on Sat Dec 16 16:07:44 GMT 2023 , Edited by admin on Sat Dec 16 16:07:44 GMT 2023

PRIMARY

NCI_THESAURUS

C2217

Created by admin on Sat Dec 16 16:07:44 GMT 2023 , Edited by admin on Sat Dec 16 16:07:44 GMT 2023

PRIMARY

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