AZAMETHONIUM BROMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H33N3.2Br
Molecular Weight	391.229
Optical Activity	NONE
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Br-].[Br-].CC[N+](C)(C)CCN(C)CC[N+](C)(C)CC

InChI

InChIKey=UPCIBFUJJLCOQG-UHFFFAOYSA-L

InChI=1S/C13H33N3.2BrH/c1-8-15(4,5)12-10-14(3)11-13-16(6,7)9-2;;/h8-13H2,1-7H3;2*1H/q+2;;/p-2

HIDE SMILES / InChI

Molecular Formula	BrH
Molecular Weight	80.912
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C13H33N3
Molecular Weight	231.4212
Charge	2
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://books.google.ru/books?id=nQclBQAAQBAJ&pg=PA534&lpg=PA534&dq=AZAMETHONIUM&source=bl&ots=SKP7deYOVp&sig=ACfU3U1bOMIguEZAL-KkvdJOCYeCavzY6Q&hl=ru&sa=X&ved=2ahUKEwjfr4SC3ePhAhVLxcQBHYbsALQ4ChDoATAGegQICBAB#v=onepage&q=AZAMETHONIUM&f=false | https://www.ncbi.nlm.nih.gov/pubmed/14897314

Azamethonium (known in Europe as pendiomid), a substance with the ganglia-blocking effect that was used in Europe to treat patients with acute pulmonary embolism. Information about the nowadays application of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
Effect of a quaternary pentamine on RNA stabilization and enzymatic methylation.	2009-09	19558320
Cu(ii) complexation with an acridine-containing macrocycle. Assembly of water cluster chains within the cavity of tetranuclear metallomacrocycles.	2009-02-21	19322495
Polyfunctional recognition of pyridinedicarboxylate anions with macrocyclic polyamine receptors containing heteroaromatic groups.	2008-11-07	18841919
In vitro and in vivo inhibition of plant polyamine oxidase activity by polyamine analogues.	2008-10	18783804
[Endocrine homeostasis and its correction with stress protectors in children with severe burn injury].	2007-04-28	17460992
Sequestration of biogenic amines by alginic and fulvic acids.	2006-08-01	16690202
Profiling preparations of recombinant birch pollen allergen Bet v 1a with capillary zone electrophoresis in pentamine modified fused-silica capillaries.	2006-07-24	16504605
New linear polyamine derivatives in spider venoms.	2005-09-01	15982700
Mechanisms of regulation of erythropoiesis during experimental neuroses.	2005-05	16224545
[Pulmonary hemorrhages of different etiology: diagnosis and treatment].	2005	15801637
99mTc-Tetraethylenepentamine-Folate--a new 99mTc-based folate derivative for the detection of folate receptor positive tumors: synthesis and biological evaluation.	2004-10	15467429
Macrocyclic polyamines deplete cellular ATP levels and inhibit cell growth in human prostate cancer cells.	2004-02-12	14761207
[Prophylaxis of endotoxicosis in the early postoperative period in patients with malignant tumors of the colon].	2003	14569783
[Action of regulators of peripheral cholinergic processes on development of early arrhythmia in myocardial ischemic rats].	2002-05-10	11998397
cis-Unsaturated analogues of 3,8,13,18,23-pentaazapentacosane (BE-4-4-4-4): synthesis and growth inhibitory effects on human prostate cancer cell lines.	2001-02-01	11462980

Sample Use Guides

In Vivo Use Guide

intravenous 20-25 mg oral: 500 mg

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:04:12 GMT 2025` Edited by `admin` on `Mon Mar 31 18:04:12 GMT 2025`
Record UNII	4K6NEI0MSR
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-28858

Preferred Name

English

AZAMETHONIUM BROMIDE

Official Name

English

azamethonium bromide [INN]

Common Name

English

AZAMETHONIUM BROMIDE [MI]

Common Name

English

((METHYLIMINO)DIETHYLENE)BIS(ETHYLDIMETHYLAMMONIUM BROMIDE)

Common Name

English

AZAMETHONIUM BROMIDE [MART.]

Common Name

English

Azamethonium bromide [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C270