AZAMETHONIUM BROMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H33N3.2Br
Molecular Weight	391.229
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Br-].[Br-].CC[N+](C)(C)CCN(C)CC[N+](C)(C)CC

InChI

InChIKey=UPCIBFUJJLCOQG-UHFFFAOYSA-L

InChI=1S/C13H33N3.2BrH/c1-8-15(4,5)12-10-14(3)11-13-16(6,7)9-2;;/h8-13H2,1-7H3;2*1H/q+2;;/p-2

HIDE SMILES / InChI

Molecular Formula	C13H33N3
Molecular Weight	231.4212
Charge	2
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	BrH
Molecular Weight	80.912
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://books.google.ru/books?id=nQclBQAAQBAJ&pg=PA534&lpg=PA534&dq=AZAMETHONIUM&source=bl&ots=SKP7deYOVp&sig=ACfU3U1bOMIguEZAL-KkvdJOCYeCavzY6Q&hl=ru&sa=X&ved=2ahUKEwjfr4SC3ePhAhVLxcQBHYbsALQ4ChDoATAGegQICBAB#v=onepage&q=AZAMETHONIUM&f=false | https://www.ncbi.nlm.nih.gov/pubmed/14897314

Azamethonium (known in Europe as pendiomid), a substance with the ganglia-blocking effect that was used in Europe to treat patients with acute pulmonary embolism. Information about the nowadays application of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
Macrocyclic polyamines deplete cellular ATP levels and inhibit cell growth in human prostate cancer cells.	2004 Feb 12	14761207
99mTc-Tetraethylenepentamine-Folate--a new 99mTc-based folate derivative for the detection of folate receptor positive tumors: synthesis and biological evaluation.	2004 Oct	15467429
In vitro and in vivo inhibition of plant polyamine oxidase activity by polyamine analogues.	2008 Oct	18783804
Cu(ii) complexation with an acridine-containing macrocycle. Assembly of water cluster chains within the cavity of tetranuclear metallomacrocycles.	2009 Feb 21	19322495
Effect of a quaternary pentamine on RNA stabilization and enzymatic methylation.	2009 Sep	19558320

Sample Use Guides

In Vivo Use Guide

intravenous 20-25 mg oral: 500 mg

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:38:57 GMT 2023` Edited by `admin` on `Fri Dec 15 15:38:57 GMT 2023`
Record UNII	4K6NEI0MSR
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AZAMETHONIUM BROMIDE

Official Name

English

azamethonium bromide [INN]

Common Name

English

AZAMETHONIUM BROMIDE [MI]

Common Name

English

((METHYLIMINO)DIETHYLENE)BIS(ETHYLDIMETHYLAMMONIUM BROMIDE)

Common Name

English

AZAMETHONIUM BROMIDE [MART.]

Common Name

English

Azamethonium bromide [WHO-DD]

Common Name

English

NSC-28858

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C270