AZAMETHONIUM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H33N3
Molecular Weight	231.4212
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	2

SHOW SMILES / InChI

Structure Search

SMILES

CC[N+](C)(C)CCN(C)CC[N+](C)(C)CC

InChI

InChIKey=NHWGPUVJQFTOQX-UHFFFAOYSA-N

InChI=1S/C13H33N3/c1-8-15(4,5)12-10-14(3)11-13-16(6,7)9-2/h8-13H2,1-7H3/q+2

HIDE SMILES / InChI

Molecular Formula	C13H33N3
Molecular Weight	231.4212
Charge	2
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://books.google.ru/books?id=nQclBQAAQBAJ&pg=PA534&lpg=PA534&dq=AZAMETHONIUM&source=bl&ots=SKP7deYOVp&sig=ACfU3U1bOMIguEZAL-KkvdJOCYeCavzY6Q&hl=ru&sa=X&ved=2ahUKEwjfr4SC3ePhAhVLxcQBHYbsALQ4ChDoATAGegQICBAB#v=onepage&q=AZAMETHONIUM&f=false | https://www.ncbi.nlm.nih.gov/pubmed/14897314

Azamethonium (known in Europe as pendiomid), a substance with the ganglia-blocking effect that was used in Europe to treat patients with acute pulmonary embolism. Information about the nowadays application of this drug is not available.

Approval Year

PubMed

Title	Date	PubMed
cis-Unsaturated analogues of 3,8,13,18,23-pentaazapentacosane (BE-4-4-4-4): synthesis and growth inhibitory effects on human prostate cancer cell lines.	2001 Feb 1	11462980
[Action of regulators of peripheral cholinergic processes on development of early arrhythmia in myocardial ischemic rats].	2002 Jan-Mar	11998397
Macrocyclic polyamines deplete cellular ATP levels and inhibit cell growth in human prostate cancer cells.	2004 Feb 12	14761207
Mechanisms of regulation of erythropoiesis during experimental neuroses.	2005 May	16224545
Sequestration of biogenic amines by alginic and fulvic acids.	2006 Aug 1	16690202
[Endocrine homeostasis and its correction with stress protectors in children with severe burn injury].	2007 Jan-Feb	17460992
Polyfunctional recognition of pyridinedicarboxylate anions with macrocyclic polyamine receptors containing heteroaromatic groups.	2008 Nov 7	18841919
In vitro and in vivo inhibition of plant polyamine oxidase activity by polyamine analogues.	2008 Oct	18783804
Cu(ii) complexation with an acridine-containing macrocycle. Assembly of water cluster chains within the cavity of tetranuclear metallomacrocycles.	2009 Feb 21	19322495
Effect of a quaternary pentamine on RNA stabilization and enzymatic methylation.	2009 Sep	19558320

Sample Use Guides

In Vivo Use Guide

intravenous 20-25 mg oral: 500 mg

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:35:14 UTC 2023` Edited by `admin` on `Fri Dec 15 15:35:14 UTC 2023`
Record UNII	43XK6AW58D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AZAMETHONIUM

Common Name

English

((METHYLIMINO)DIETHYLENE)BIS(ETHYLDIMETHYLAMMONIUM)

Systematic Name

English

AZAMETHONIUM ION

Common Name

English

Azamethonium [WHO-DD]

Common Name

English

AZAMETHONIUM CATION

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66886