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Details

Stereochemistry RACEMIC
Molecular Formula C6H10O7
Molecular Weight 194.1394
Optical Activity ( + / - )
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GALACTURONIC ACID, DL-

SMILES

O[C@@H](C=O)[C@@H](O)[C@@H](O)[C@H](O)C(O)=O

InChI

InChIKey=IAJILQKETJEXLJ-RSJOWCBRSA-N
InChI=1S/C6H10O7/c7-1-2(8)3(9)4(10)5(11)6(12)13/h1-5,8-11H,(H,12,13)/t2-,3+,4+,5-/m0/s1

HIDE SMILES / InChI

Molecular Formula C6H10O7
Molecular Weight 194.1394
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

D-Galacturonic acid is the main constituent of pectin, a naturally abundant compound. It is the monobasic acid resulting from oxidation of the primary alcohol group of D-galactose to carboxyl. D-Galacturonic acid prepared from pectin can be used to synthesize vitamin C. Native pectin is a mixture of polysaccharides, with the major component a polymer of -D-galacturonic acid. Pectin has numerous other medical and pharmaceutical uses, for example in combination with plant hemicelluloses and lignin, may be useful dietary constituents in preventing coronary heart disease, diverticular disease, ulcerative colitis, and a variety of other Western diseases. Pectin, a representative diety fibre, is a gelatinous substance derived from the cell walls of fruits and some plants and contains galacturonan, consisting of mostly long-chain D-galacturonic acids combined into units by α-1,4 linkages. As a kind of soluble dietary fiber, pectin has been proved of controlling glucose and blood lipids. It slows rapid infusion of the liquid meal into the gut by delaying gastric emptying.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Purification and biochemical characterization of polygalacturonases produced by Aureobasidium pullulans.
2005 Jan-Feb
Wound healing evaluation of sodium fucidate-loaded polyvinylalcohol/sodium carboxymethylcellulose-based wound dressing.
2010 Jul
Patents

Sample Use Guides

Guinea pigs: The animals were divided into three groups: Group I, positivecontrols; Group II, negative controls; Group III, experimental,with three different methods of administering the d-galacturonicacid-Group III-a, orally, by pipette (5 mg); Group III-b, subcutaneousinjection (5 mg); Group III-c, intraperitoneal injection (10 mg). Three of thepositive controls were given, in addition to their regular diet,5 mg of d-galacturonic acid daily.
Route of Administration: Other
Galacturonic acid at 2 mM induced the production of some of the pectic enzymes by Botrytis cinerea. At 10 mM and above, however, it repressed PG2 and the subsequent production of the whole pectic isoenzyme complex, indicating a feedback repression.
Substance Class Chemical
Created
by admin
on Fri Dec 15 20:38:43 UTC 2023
Edited
by admin
on Fri Dec 15 20:38:43 UTC 2023
Record UNII
4JK6RN80GF
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GALACTURONIC ACID, DL-
Common Name English
DL-GALACTURONIC ACID
Common Name English
Code System Code Type Description
MESH
C007819
Created by admin on Fri Dec 15 20:38:43 UTC 2023 , Edited by admin on Fri Dec 15 20:38:43 UTC 2023
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WIKIPEDIA
Galacturonic acid
Created by admin on Fri Dec 15 20:38:43 UTC 2023 , Edited by admin on Fri Dec 15 20:38:43 UTC 2023
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CAS
14982-50-4
Created by admin on Fri Dec 15 20:38:43 UTC 2023 , Edited by admin on Fri Dec 15 20:38:43 UTC 2023
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ECHA (EC/EINECS)
239-061-5
Created by admin on Fri Dec 15 20:38:43 UTC 2023 , Edited by admin on Fri Dec 15 20:38:43 UTC 2023
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PUBCHEM
84740
Created by admin on Fri Dec 15 20:38:43 UTC 2023 , Edited by admin on Fri Dec 15 20:38:43 UTC 2023
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EPA CompTox
DTXSID00873872
Created by admin on Fri Dec 15 20:38:43 UTC 2023 , Edited by admin on Fri Dec 15 20:38:43 UTC 2023
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FDA UNII
4JK6RN80GF
Created by admin on Fri Dec 15 20:38:43 UTC 2023 , Edited by admin on Fri Dec 15 20:38:43 UTC 2023
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