3-HYDROXY-2,2-DIMETHYL-N-(4-((5-(METHYLAMINO)-1-NAPHTHYL)SULFONYLAMINO)PHENYL)PROPANAMIDE

CNC1=C2C=CC=C(C2=CC=C1)S(=O)(=O)NC3=CC=C(NC(=O)C(C)(C)CO)C=C3

InChIKey=YUJQCLQKLOZLMR-UHFFFAOYSA-N

InChI=1S/C22H25N3O4S/c1-22(2,14-26)21(27)24-15-10-12-16(13-11-15)25-30(28,29)20-9-5-6-17-18(20)7-4-8-19(17)23-3/h4-13,23,25-26H,14H2,1-3H3,(H,24,27)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:29:49 GMT 2023` Edited by `admin` on `Sat Dec 16 11:29:49 GMT 2023`
Record UNII	4FH3T4XF5H
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

3-HYDROXY-2,2-DIMETHYL-N-(4-((5-(METHYLAMINO)-1-NAPHTHYL)SULFONYLAMINO)PHENYL)PROPANAMIDE

Systematic Name

English

BAY-43-9695

Common Name

English

PROPANAMIDE, 3-HYDROXY-2,2-DIMETHYL-N-(4-(((5-(METHYLAMINO)-1-NAPHTHALENYL)SULFONYL)AMINO)PHENYL)-

Systematic Name

English

Code System Code Type Description

FDA UNII

4FH3T4XF5H

Created by admin on Sat Dec 16 11:29:50 GMT 2023 , Edited by admin on Sat Dec 16 11:29:50 GMT 2023

PRIMARY

CAS

233255-39-5

Created by admin on Sat Dec 16 11:29:50 GMT 2023 , Edited by admin on Sat Dec 16 11:29:50 GMT 2023

PRIMARY

PUBCHEM

475818

Created by admin on Sat Dec 16 11:29:50 GMT 2023 , Edited by admin on Sat Dec 16 11:29:50 GMT 2023

PRIMARY

Related Record Type Details


					4FH3T4XF5H

ACTIVE MOIETY

Comments:

The FACS assay yield average IC50 of BAY43-9695 for the AD169 laboratory strain of 0.95 +- (mean +-0.17 standard deviation) was 0.30 +- 0.21 M.