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Details

Stereochemistry ACHIRAL
Molecular Formula C14H31NO
Molecular Weight 229.402
Optical Activity NONE
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LAURAMINE OXIDE

SMILES

CCCCCCCCCCCC[N+](C)(C)[O-]

InChI

InChIKey=SYELZBGXAIXKHU-UHFFFAOYSA-N
InChI=1S/C14H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-15(2,3)16/h4-14H2,1-3H3

HIDE SMILES / InChI

Molecular Formula C14H31NO
Molecular Weight 229.402
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity NONE

Lauramine Oxide is a tertiary amine oxide. Because Lauramine Oxide has dual functional groups in the same molecule (both asidic and basic groups), it is very versatile. At a concentration of 30%, Lauramine Oxide produced severe dermal reactions in rabbits, but at 0.3% only slight to moderate erythema with slight edema. Lauramine Oxide at 0.1% in drinking water was not carcinogenic in rats. Lauramine oxide is used mainly in hair-care products such as shampoos, hair rinses, tonics and hair-grooming aids.

Approval Year

PubMed

PubMed

TitleDatePubMed
Pycnogenol and Ginkgo biloba extract: effect on peroxynitrite-oxidized sarcoplasmic reticulum Ca-ATPase.
2010-12
Complexation of phenol and thiophenol by amine N-oxides: isothermal titration calorimetry and ab initio calculations.
2010-11-15
Effect of nanoparticle size on the morphology of adsorbed surfactant layers.
2010-04-01
Backbone and ILV side chain methyl group assignments of the integral human membrane protein VDAC-1.
2010-04
Two different hematocrit detection methods: different methods, different results?
2010-03-09
Reflections on my career in analytical chemistry and biochemistry.
2010
Structure and non-essential function of glycerol kinase in Plasmodium falciparum blood stages.
2009-01
Structural characterization of recombinant human CD81 produced in Pichia pastoris.
2008-02
Theoretical predictions of the coordination of water to the polar headgroup of dimethyldodecylamine-N-oxide.
2007-03-12
Overexpression and purification of the RyR1 pore-forming region.
2007
Hydration of dimethyldodecylamine-N-oxide: enthalpy and entropy driven processes.
2006-07-13
Purification, crystallization, and properties of F1-ATPase complexes from the thermoalkaliphilic Bacillus sp. strain TA2.A1.
2005-11
Thermodynamic study of the protonation of dimethyldodecylamine N-oxide micelles in aqueous solution at 298 K. Establishment of a theoretical relationship linking critical micelle concentrations and pH.
2004-09-28
The ionic track in the F1-ATPase from the thermophilic Bacillus PS3.
2004-03-09
Resolution of the V1 ATPase from Manduca sexta into subcomplexes and visualization of an ATPase-active A3B3EG complex by electron microscopy.
2003-01-03
The (alpha F(357)C)(3)(beta R(372)C)(3)gamma subcomplex of the F(1)-ATPase from the thermophilic Bacillus PS3 has altered ATPase activity after cross-linking alpha and beta subunits at noncatalytic site interfaces.
2002-03-05
Modulation of hepatitis C virus NS3 protease and helicase activities through the interaction with NS4A.
1999-04-27
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:35:01 GMT 2025
Edited
by admin
on Mon Mar 31 17:35:01 GMT 2025
Record UNII
4F6FC4MI8W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
EMPIGEN OB
Preferred Name English
LAURAMINE OXIDE
HSDB   II   INCI  
INCI  
Official Name English
LAURYL DIMETHYL AMINE OXIDE
Systematic Name English
N,N-DIMETHYLDODECYLAMINE N-OXIDE
Systematic Name English
EUROXIDE LO
Common Name English
LAURAMINE OXIDE [II]
Common Name English
1-DODECANAMINE, N,N-DIMETHYL-, N-OXIDE
Systematic Name English
LAURAMINE OXIDE [HSDB]
Common Name English
DODECYLDIMETHYLAMINE OXIDE
Systematic Name English
LAURYLAMINE OXIDE
Systematic Name English
N,N-DIMETHYL LAURAMINE OXIDE
Common Name English
LAURYLDIMETHYLAMINE OXIDE
Systematic Name English
N,N-DIMETHYL-1-DODECANAMINE-N-OXIDE
Systematic Name English
Code System Code Type Description
MESH
C014518
Created by admin on Mon Mar 31 17:35:01 GMT 2025 , Edited by admin on Mon Mar 31 17:35:01 GMT 2025
PRIMARY
RXCUI
1364388
Created by admin on Mon Mar 31 17:35:01 GMT 2025 , Edited by admin on Mon Mar 31 17:35:01 GMT 2025
PRIMARY RxNorm
ECHA (EC/EINECS)
216-700-6
Created by admin on Mon Mar 31 17:35:01 GMT 2025 , Edited by admin on Mon Mar 31 17:35:01 GMT 2025
PRIMARY
DRUG BANK
DB04147
Created by admin on Mon Mar 31 17:35:01 GMT 2025 , Edited by admin on Mon Mar 31 17:35:01 GMT 2025
PRIMARY
WIKIPEDIA
LAURYLDIMETHYLAMINE OXIDE
Created by admin on Mon Mar 31 17:35:01 GMT 2025 , Edited by admin on Mon Mar 31 17:35:01 GMT 2025
PRIMARY
EPA CompTox
DTXSID1020514
Created by admin on Mon Mar 31 17:35:01 GMT 2025 , Edited by admin on Mon Mar 31 17:35:01 GMT 2025
PRIMARY
PUBCHEM
15433
Created by admin on Mon Mar 31 17:35:01 GMT 2025 , Edited by admin on Mon Mar 31 17:35:01 GMT 2025
PRIMARY
EVMPD
SUB21624
Created by admin on Mon Mar 31 17:35:01 GMT 2025 , Edited by admin on Mon Mar 31 17:35:01 GMT 2025
PRIMARY
CHEBI
131762
Created by admin on Mon Mar 31 17:35:01 GMT 2025 , Edited by admin on Mon Mar 31 17:35:01 GMT 2025
PRIMARY
DAILYMED
4F6FC4MI8W
Created by admin on Mon Mar 31 17:35:01 GMT 2025 , Edited by admin on Mon Mar 31 17:35:01 GMT 2025
PRIMARY
HSDB
5451
Created by admin on Mon Mar 31 17:35:01 GMT 2025 , Edited by admin on Mon Mar 31 17:35:01 GMT 2025
PRIMARY
FDA UNII
4F6FC4MI8W
Created by admin on Mon Mar 31 17:35:01 GMT 2025 , Edited by admin on Mon Mar 31 17:35:01 GMT 2025
PRIMARY
CAS
1643-20-5
Created by admin on Mon Mar 31 17:35:01 GMT 2025 , Edited by admin on Mon Mar 31 17:35:01 GMT 2025
PRIMARY
SMS_ID
100000088316
Created by admin on Mon Mar 31 17:35:01 GMT 2025 , Edited by admin on Mon Mar 31 17:35:01 GMT 2025
PRIMARY
Related Record Type Details
ACTIVE MOIETY