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Details

Stereochemistry ACHIRAL
Molecular Formula C20H25NO3
Molecular Weight 327.4174
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIMENOXADOL

SMILES

CCOC(C(=O)OCCN(C)C)(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=RHUWRJWFHUKVED-UHFFFAOYSA-N
InChI=1S/C20H25NO3/c1-4-24-20(17-11-7-5-8-12-17,18-13-9-6-10-14-18)19(22)23-16-15-21(2)3/h5-14H,4,15-16H2,1-3H3

HIDE SMILES / InChI
Molecular Formula C20H25NO3
Molecular Weight 327.4174
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Dimenoxadol is an opioid analgesic which produces typical opioid effects such as analgesia and sedation. It is structurally similar to methadone and is a benzilic acid derivative. In the United States it is classified as a Schedule I controlled drug.

CNS Activity

CNS Active
4,002

Originator

Boehringer, A. et al.
1

Approval Year

Unknown
149,124

Targets

Primary TargetPharmacologyConditionPotency
Opioid receptors; mu/kappa/delta
33
Agonist
2,752

Conditions

ConditionModalityTargetsHighest PhaseProduct
Pain
619
 Palliative
Preclinical
Unknown

PubMed

Patents

JP2005530798A
42
JP4642467B2
32

Sample Use Guides

In Vivo Use Guide
LD50 i.v. in rats: 66 mg/kg
Route of Administration: Intravenous
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
4D65PBX0VK
Record Status Validated (UNII)
Record Version
NIH
NCATS
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