DIMENOXADOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H25NO3
Molecular Weight	327.4174
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(C(=O)OCCN(C)C)(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=RHUWRJWFHUKVED-UHFFFAOYSA-N

InChI=1S/C20H25NO3/c1-4-24-20(17-11-7-5-8-12-17,18-13-9-6-10-14-18)19(22)23-16-15-21(2)3/h5-14H,4,15-16H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C20H25NO3
Molecular Weight	327.4174
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5232927 | https://www.drugbank.ca/drugs/DB01461 | https://www.ncbi.nlm.nih.gov/pubmed/5729519

Dimenoxadol is an opioid analgesic which produces typical opioid effects such as analgesia and sedation. It is structurally similar to methadone and is a benzilic acid derivative. In the United States it is classified as a Schedule I controlled drug.

CNS Activity

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Opioid receptors; mu/kappa/delta 33 Target ID: CHEMBL2095181 Sources: http://www.behavenet.com/dimenoxadol	Agonist 2678

Conditions

Condition	Modality	Targets	Highest Phase	Product
Pain 614 Sources: https://www.ncbi.nlm.nih.gov/pubmed/5232927 https://www.ncbi.nlm.nih.gov/pubmed/5729519	Palliative		Preclinical	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
[Pharmacology of dimethylaminoethyl ester of diphenylethoxyacetic acid hydrochloride--estocin].	1969 Nov-Dec	5381602

Patents

Sample Use Guides

In Vivo Use Guide

LD50 i.v. in rats: 66 mg/kg

Route of Administration: Intravenous

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:34:24 GMT 2023` Edited by `admin` on `Fri Dec 15 16:34:24 GMT 2023`
Record UNII	4D65PBX0VK
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DIMENOXADOL

Official Name

English

DIMENOXADOLE

Common Name

English

IDS-ND-011

Code

English

DIMENOXADOL [MI]

Common Name

English

2-DIMETHYLAMINOETHYL 1-ETHOXY-1,1-DIPHENYLACETATE

Common Name

English

ETHOXYDIPHENYLACETIC ACID 2-DIMETHYLAMINOETHYL ESTER

Systematic Name

English

BENZENEACETIC ACID, .ALPHA.-ETHOXY-.ALPHA.-PHENYL-, 2-(DIMETHYLAMINO)ETHYL ESTER

Systematic Name

English

dimenoxadol [INN]

Common Name

English

ACETIC ACID, ETHOXYDIPHENYL-, 2-(DIMETHYLAMINO)ETHYL ESTER

Common Name

English

ACSCN-9617

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C241