DIMECOLONIUM IODIDE

Details

Stereochemistry	MIXED
Molecular Formula	C14H30N2O2.2I
Molecular Weight	512.2091
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[I-].[I-].CC1CCCC(C(=O)OCC[N+](C)(C)C)[N+]1(C)C

InChI

InChIKey=UZOHFHFMSPULPR-UHFFFAOYSA-L

InChI=1S/C14H30N2O2.2HI/c1-12-8-7-9-13(16(12,5)6)14(17)18-11-10-15(2,3)4;;/h12-13H,7-11H2,1-6H3;2*1H/q+2;;/p-2

HIDE SMILES / InChI

Molecular Formula	C14H30N2O2
Molecular Weight	258.4002
Charge	2
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	HI
Molecular Weight	127.91241
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6154492 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 427, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ

Dimecolonium is the N-cholinolytic drug. It is the ganglion-blocking agent. The functional activity in some ganglioid neurones increases after administration of various doses of dimecolin during the blockade and after its termination.

Approval Year

Patents

Sample Use Guides

In Vivo Use Guide

Single dose - 10, 30 and 50 mg/kg

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:18:56 GMT 2025` Edited by `admin` on `Mon Mar 31 18:18:56 GMT 2025`
Record UNII	4D4NC8MXLW
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIMECOLONIUM IODIDE

Official Name

English

DIMEKOLIN

Preferred Name

English

ESTER OF 2-CARBOXY-1,1,6-TRIMETHYLPIPERIDINIUM IODIDE WITH (2-HYDROXYETHYL) TRIMETHYLAMMONIUM IODIDE

Common Name

English

dimecolonium iodide [INN]

Common Name

English

DIMELIN

Common Name

English

PIPERIDINIUM, 1,1,2-TRIMETHYL-6-((2-(TRIMETHYLAMMONIO)ETHOXY)CARBONYL)-, IODIDE (1:2)

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66886