GSK-2256098 HYDROCHLORIDE

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H23ClN6O2.ClH
Molecular Weight	451.35
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CONC(=O)C1=CC=CC=C1NC2=C(Cl)C=NC(NC3=CC(C)=NN3C(C)C)=C2

InChI

InChIKey=KWSGTBMHVKYZMA-UHFFFAOYSA-N

InChI=1S/C20H23ClN6O2.ClH/c1-12(2)27-19(9-13(3)25-27)24-18-10-17(15(21)11-22-18)23-16-8-6-5-7-14(16)20(28)26-29-4;/h5-12H,1-4H3,(H,26,28)(H2,22,23,24);1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C20H23ClN6O2
Molecular Weight	414.889
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Focal adhesion kinase 1 13 Target ID: CHEMBL2695 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25486573	Inhibitor 8504		15.0 nM [IC50]

PubMed

Title	Date	PubMed
A small molecule FAK kinase inhibitor, GSK2256098, inhibits growth and survival of pancreatic ductal adenocarcinoma cells.	2014	25486573

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:11:52 GMT 2025` Edited by `admin` on `Mon Mar 31 22:11:52 GMT 2025`
Record UNII	4CSJ8BJ597
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GSK-2256098 HYDROCHLORIDE

Code

English

BENZAMIDE, 2-((5-CHLORO-2-((3-METHYL-1-(1-METHYLETHYL)-1H-PYRAZOL-5-YL)AMINO)-4-PYRIDINYL)AMINO)-N-METHOXY-, HYDROCHLORIDE (1:1)

Preferred Name

English

Code System Code Type Description

FDA UNII

4CSJ8BJ597

Created by admin on Mon Mar 31 22:11:52 GMT 2025 , Edited by admin on Mon Mar 31 22:11:52 GMT 2025

PRIMARY

PUBCHEM

54589075

Created by admin on Mon Mar 31 22:11:52 GMT 2025 , Edited by admin on Mon Mar 31 22:11:52 GMT 2025

PRIMARY

CAS

1416771-10-2

Created by admin on Mon Mar 31 22:11:52 GMT 2025 , Edited by admin on Mon Mar 31 22:11:52 GMT 2025

PRIMARY

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ACTIVE MOIETY