FR-188582

CS(=O)(=O)C1=CC=C(C=C1)C2=CC(Cl)=NN2C3=CC=CC=C3

InChIKey=YKHNOHGHDAQJFW-UHFFFAOYSA-N

InChI=1S/C16H13ClN2O2S/c1-22(20,21)14-9-7-12(8-10-14)15-11-16(17)18-19(15)13-5-3-2-4-6-13/h2-11H,1H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Effects of intravenous administration of FR122047 (a selective cyclooxygenase 1 inhibitor) and FR188582 (a selective cyclooxygenase 2 inhibitor) on prostaglandin-E2-induced aqueous flare elevation in pigmented rabbits.	2003-12-23	15627832
The anti-inflammatory effect of FR188582, a highly selective inhibitor of cyclooxygenase-2, with an ulcerogenic sparing effect in rats.	2001-02	11286400

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:36:20 GMT 2025` Edited by `admin` on `Mon Mar 31 22:36:20 GMT 2025`
Record UNII	49893L163S
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

1H-PYRAZOLE, 3-CHLORO-5-(4-(METHYLSULFONYL)PHENYL)-1-PHENYL-

Preferred Name

English

FR-188582

Common Name

English

Code System Code Type Description

FDA UNII

49893L163S

Created by admin on Mon Mar 31 22:36:20 GMT 2025 , Edited by admin on Mon Mar 31 22:36:20 GMT 2025

PRIMARY

CAS

189699-82-9

Created by admin on Mon Mar 31 22:36:20 GMT 2025 , Edited by admin on Mon Mar 31 22:36:20 GMT 2025

PRIMARY

PUBCHEM

9840588

Created by admin on Mon Mar 31 22:36:20 GMT 2025 , Edited by admin on Mon Mar 31 22:36:20 GMT 2025

PRIMARY

Related Record Type Details


					49893L163S

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