Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C8H18N4O2 |
| Molecular Weight | 202.2541 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CNC(NC)=NCCC[C@H](N)C(O)=O
InChI
InChIKey=HVPFXCBJHIIJGS-LURJTMIESA-N
InChI=1S/C8H18N4O2/c1-10-8(11-2)12-5-3-4-6(9)7(13)14/h6H,3-5,9H2,1-2H3,(H,13,14)(H2,10,11,12)/t6-/m0/s1
| Molecular Formula | C8H18N4O2 |
| Molecular Weight | 202.2541 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Elevations of plasma methylarginines in obesity and ageing are related to insulin sensitivity and rates of protein turnover. | 2006-02 |
|
| Relations between plasma asymmetric dimethylarginine (ADMA) and risk factors for coronary disease. | 2006-02 |
|
| Regular physical exercise normalizes elevated asymmetrical dimethylarginine concentrations in patients with type 1 diabetes mellitus. | 2005-12 |
|
| Circulating ADMA concentrations are elevated in hypopituitary adults with and without growth hormone deficiency. | 2005-03 |
|
| Acute Escherichia coli endotoxaemia decreases the plasma l-arginine/asymmetrical dimethylarginine ratio in humans. | 2004-06 |
|
| Serum concentrations of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine in patients with chronic kidney diseases. | 2003-10 |
|
| Effect of smoking on risk factors for cardiovascular disease in patients with diabetes mellitus and renal insufficiency. | 2003-07-31 |
|
| Oestrogen replacement therapy lowers plasma levels of asymmetrical dimethylarginine in healthy postmenopausal women. | 2003-07 |
|
| Net renal extraction of asymmetrical (ADMA) and symmetrical (SDMA) dimethylarginine in fasting humans. | 2002-11 |
|
| Levels of dimethylarginines and cytokines in mild and severe preeclampsia. | 2001-07 |
|
| Total nitric oxide production is low in patients with chronic renal disease. | 2000-09 |
|
| Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia. | 1998-11-03 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:46:44 GMT 2025
by
admin
on
Mon Mar 31 22:46:44 GMT 2025
|
| Record UNII |
49787G1ULV
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
30344-00-4
Created by
admin on Mon Mar 31 22:46:44 GMT 2025 , Edited by admin on Mon Mar 31 22:46:44 GMT 2025
|
PRIMARY | |||
|
169148
Created by
admin on Mon Mar 31 22:46:44 GMT 2025 , Edited by admin on Mon Mar 31 22:46:44 GMT 2025
|
PRIMARY | |||
|
49787G1ULV
Created by
admin on Mon Mar 31 22:46:44 GMT 2025 , Edited by admin on Mon Mar 31 22:46:44 GMT 2025
|
PRIMARY | |||
|
25682
Created by
admin on Mon Mar 31 22:46:44 GMT 2025 , Edited by admin on Mon Mar 31 22:46:44 GMT 2025
|
PRIMARY | |||
|
C185348
Created by
admin on Mon Mar 31 22:46:44 GMT 2025 , Edited by admin on Mon Mar 31 22:46:44 GMT 2025
|
PRIMARY | |||
|
DTXSID00952691
Created by
admin on Mon Mar 31 22:46:44 GMT 2025 , Edited by admin on Mon Mar 31 22:46:44 GMT 2025
|
PRIMARY | |||
|
DB02302
Created by
admin on Mon Mar 31 22:46:44 GMT 2025 , Edited by admin on Mon Mar 31 22:46:44 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
PRODRUG -> METABOLITE ACTIVE |
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ACTIVE MOIETY |
|
