Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C8H18N4O2 |
| Molecular Weight | 202.2541 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CNC(NC)=NCCC[C@H](N)C(O)=O
InChI
InChIKey=HVPFXCBJHIIJGS-LURJTMIESA-N
InChI=1S/C8H18N4O2/c1-10-8(11-2)12-5-3-4-6(9)7(13)14/h6H,3-5,9H2,1-2H3,(H,13,14)(H2,10,11,12)/t6-/m0/s1
| Molecular Formula | C8H18N4O2 |
| Molecular Weight | 202.2541 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia. | 1998 Nov 3 |
|
| Total nitric oxide production is low in patients with chronic renal disease. | 2000 Sep |
|
| Levels of dimethylarginines and cytokines in mild and severe preeclampsia. | 2001 Jul |
|
| Oestrogen replacement therapy lowers plasma levels of asymmetrical dimethylarginine in healthy postmenopausal women. | 2003 Jul |
|
| Regular physical exercise normalizes elevated asymmetrical dimethylarginine concentrations in patients with type 1 diabetes mellitus. | 2005 Dec |
|
| Circulating ADMA concentrations are elevated in hypopituitary adults with and without growth hormone deficiency. | 2005 Mar |
|
| Relations between plasma asymmetric dimethylarginine (ADMA) and risk factors for coronary disease. | 2006 Feb |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:40:16 GMT 2023
by
admin
on
Sat Dec 16 09:40:16 GMT 2023
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| Record UNII |
49787G1ULV
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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30344-00-4
Created by
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169148
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49787G1ULV
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25682
Created by
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C185348
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DTXSID00952691
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DB02302
Created by
admin on Sat Dec 16 09:40:16 GMT 2023 , Edited by admin on Sat Dec 16 09:40:16 GMT 2023
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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PRODRUG -> METABOLITE ACTIVE |
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
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