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Details

Stereochemistry ABSOLUTE
Molecular Formula C14H14O3
Molecular Weight 230.2592
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NAPROXEN, (-)-

SMILES

COC1=CC2=CC=C(C=C2C=C1)[C@@H](C)C(O)=O

InChI

InChIKey=CMWTZPSULFXXJA-SECBINFHSA-N
InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m1/s1

HIDE SMILES / InChI
Molecular Formula C14H14O3
Molecular Weight 230.2592
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

(R)-Naproxen is an enantiomer of the more active (S)-Naproxen, the last belongs to the class of Non-Steroidal Anti-Inflammatory Drugs. (S)- and (R)-naproxen represent useful substrates to distinguish different glucuronosyl transferases isozymes.

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Substrate
661
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Patents

Patents

JP2008504356A
31

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:34:58 UTC 2023
Edited
by admin
on Sat Dec 16 08:34:58 UTC 2023
Record UNII
484XV9323P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NAPROXEN, (-)-
Common Name English
NAPROXEN IMPURITY G [EP IMPURITY]
Common Name English
L-NAPROXEN
Common Name English
NAPROXEN SODIUM IMPURITY G [EP IMPURITY]
Common Name English
2-NAPHTHALENEACETIC ACID, 6-METHOXY-.ALPHA.-METHYL-, (.ALPHA.R)-
Systematic Name English
(R)-(-)-NAPROXEN
Common Name English
NAPROXEN RELATED COMPOUND G [USP-RS]
Common Name English
(2R)-2-(6-METHOXYNAPHTHALEN-2-YL)PROPANOIC ACID
Systematic Name English
(-)-6-METHOXY-.ALPHA.-METHYL-2-NAPHTHALENEACETIC ACID
Systematic Name English
(R)-NAPROXEN
Common Name English
Code System Code Type Description
ECHA (EC/EINECS)
245-966-6
Created by admin on Sat Dec 16 08:34:59 UTC 2023 , Edited by admin on Sat Dec 16 08:34:59 UTC 2023
PRIMARY
CAS
23979-41-1
Created by admin on Sat Dec 16 08:34:59 UTC 2023 , Edited by admin on Sat Dec 16 08:34:59 UTC 2023
PRIMARY
RS_ITEM_NUM
1457436
Created by admin on Sat Dec 16 08:34:59 UTC 2023 , Edited by admin on Sat Dec 16 08:34:59 UTC 2023
PRIMARY
PUBCHEM
169118
Created by admin on Sat Dec 16 08:34:59 UTC 2023 , Edited by admin on Sat Dec 16 08:34:59 UTC 2023
PRIMARY
EPA CompTox
DTXSID00904711
Created by admin on Sat Dec 16 08:34:59 UTC 2023 , Edited by admin on Sat Dec 16 08:34:59 UTC 2023
PRIMARY
FDA UNII
484XV9323P
Created by admin on Sat Dec 16 08:34:59 UTC 2023 , Edited by admin on Sat Dec 16 08:34:59 UTC 2023
PRIMARY
Related Record Type Details
Structure of NAPROXEN SODIUM
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of NAPROXEN
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
NIH
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