NICOFIBRATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H16ClNO3
Molecular Weight	305.756
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(OC1=CC=C(Cl)C=C1)C(=O)OCC2=CC=CN=C2

InChI

InChIKey=RARQHAFNGNPQCZ-UHFFFAOYSA-N

InChI=1S/C16H16ClNO3/c1-16(2,21-14-7-5-13(17)6-8-14)15(19)20-11-12-4-3-9-18-10-12/h3-10H,11H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C16H16ClNO3
Molecular Weight	305.756
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/323747 | https://www.drugfuture.com/chemdata/nicofibrate.html

Nicofibrate is an antilipidemic drug. Treatment of diabetics led to a significant reduction in plasma cholesterol and triglycerides and brought the lipoprotein picture back within the norm. Nicofibrate did not lead to significant increases in uricaemia nor to any worsening in carbohydrate tolerance. Nicofibrate may also lead to a significant drop in plasma prothrombinic activity.

Originator

Approval Year

PubMed

Title	Date	PubMed
[Therapeutic effects of nicofibrate on diabetic hyperlipemia].	1977 Apr 21	323747

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:56:53 GMT 2023` Edited by `admin` on `Fri Dec 15 15:56:53 GMT 2023`
Record UNII	4839MB71E7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NICOFIBRATE

Official Name

English

Nicofibrate [WHO-DD]

Common Name

English

3-PYRIDYLMETHYL 2-(P-CHLOROPHENOXY)-2-METHYLPROPIONATE

Common Name

English

NICOFIBRATE [MI]

Common Name

English

nicofibrate [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C98150