FUBROGONIUM IODIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C14H23BrNO3.I
Molecular Weight	460.146
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[I-].CC[N+](C)(CC)CCC(C)OC(=O)C1=CC=C(Br)O1

InChI

InChIKey=KROWHJNUJMVHNU-UHFFFAOYSA-M

InChI=1S/C14H23BrNO3.HI/c1-5-16(4,6-2)10-9-11(3)18-14(17)12-7-8-13(15)19-12;/h7-8,11H,5-6,9-10H2,1-4H3;1H/q+1;/p-1

HIDE SMILES / InChI

Molecular Formula	HI
Molecular Weight	127.9124
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C14H23BrNO3
Molecular Weight	333.241
Charge	1
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13865362 | https://www.ncbi.nlm.nih.gov/pubmed/13931046 | https://www.webapteka.ru/drugbase/name7133.html

Fubromegan, a ganglionic blocking agent as an iodide salt, FUBROGONIUM IODIDE was used in Russia in patients with peptic ulcer and in the symptomatic therapy of patients with pneumoconioses. The antispasmodic effect of fubromegan was due to the effect on m- and n-cholinergic structures of smooth muscles and ganglia.

Approval Year

PubMed

Title	Date	PubMed
[Roentgenological studies on the effect of fubromegan in dyskinesias of the biliary tract].	1961	14481654
[Quateleron and Fubromegan in the treatment of peptic ulcer].	1961 Dec	14470765
[Effect of fubromegan on the motor-evacuation activity of the stomach (roentgenological studies)].	1961 Nov	14464241
[Use of a new domestic preparation fubromegan in the treatment of peptic ulcer].	1961 Nov	14474907
[COMPARATIVE EVALUATION OF THE EFFECT OF CHOLINOLYTIC DRUGS (HEXONIUM, FUBROMEGAN AND QUATALERON) ON THE DEVELOPMENT OF EXPERIMENTAL ULCER].	1963 Nov-Dec	14176177

Patents

Sample Use Guides

In Vivo Use Guide

the initial dosage: 30 mg with increasing up to 60-100 мmg. 2-3 times/day during 2-3 weeks

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:08:14 GMT 2023` Edited by `admin` on `Fri Dec 15 16:08:14 GMT 2023`
Record UNII	4791MN0PVE
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FUBROGONIUM IODIDE

Official Name

English

fubrogonium iodide [INN]

Common Name

English

DIETHYL (3-HYDROXYBUTYL)METHYLAMMONIUM IODIDE 5-BROMO-2-FUROATE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29696