Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H19ClN4O |
| Molecular Weight | 342.823 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=NC(N[C@H]2CC[C@H](O)CC2)=C(C=N1)C#CC3=CC=C(Cl)C=C3
InChI
InChIKey=XBVOXAWRUIZEMG-WKILWMFISA-N
InChI=1S/C18H19ClN4O/c19-14-5-2-12(3-6-14)1-4-13-11-21-18(20)23-17(13)22-15-7-9-16(24)10-8-15/h2-3,5-6,11,15-16,24H,7-10H2,(H3,20,21,22,23)/t15-,16-
| Molecular Formula | C18H19ClN4O |
| Molecular Weight | 342.823 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Wide spectrum modulation by KP-544 in models relevant for neuronal survival. | 2007-04-16 |
|
| The novel substituted pyrimidine, KP544, reduces motor deficits in the R6/2 transgenic mouse model of Huntington's disease. | 2007 |
|
| Neurotrophic enhancers as therapy for behavioral deficits in rodent models of Huntington's disease: use of gangliosides, substituted pyrimidines, and mesenchymal stem cells. | 2006-06 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 11:33:21 GMT 2025
by
admin
on
Wed Apr 02 11:33:21 GMT 2025
|
| Record UNII |
44CE82289R
|
| Record Status |
Validated (UNII)
|
| Record Version |
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Download
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Preferred Name | English | ||
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Common Name | English |
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9902638
Created by
admin on Wed Apr 02 11:33:21 GMT 2025 , Edited by admin on Wed Apr 02 11:33:21 GMT 2025
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PRIMARY | |||
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393856-87-6
Created by
admin on Wed Apr 02 11:33:21 GMT 2025 , Edited by admin on Wed Apr 02 11:33:21 GMT 2025
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PRIMARY | |||
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44CE82289R
Created by
admin on Wed Apr 02 11:33:21 GMT 2025 , Edited by admin on Wed Apr 02 11:33:21 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
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TARGET -> ACTIVATOR |
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| Related Record | Type | Details | ||
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ACTIVE MOIETY |
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