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Details

Stereochemistry RACEMIC
Molecular Formula C13H14N2O3
Molecular Weight 246.2619
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N-ACETYL-DL-TRYPTOPHAN

SMILES

CC(=O)NC(CC1=CNC2=C1C=CC=C2)C(O)=O

InChI

InChIKey=DZTHIGRZJZPRDV-UHFFFAOYSA-N
InChI=1S/C13H14N2O3/c1-8(16)15-12(13(17)18)6-9-7-14-11-5-3-2-4-10(9)11/h2-5,7,12,14H,6H2,1H3,(H,15,16)(H,17,18)

HIDE SMILES / InChI

Molecular Formula C13H14N2O3
Molecular Weight 246.2619
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Acetyltryptophan,DL- functions readily as a component of the food in place of the free amino acid - a greater amount of acetyltryptophane,DL- than dl-tryptophane may be available to man. Acetyltryptophan,DL- is used as an additive in the protein microbubbles, used in various biomedical applications such as contrast imaging, targeted drug and gene delivery, delivery of drugs through blood brain barrier (BBB) and IV O2 delivery etc. In the breast cancer biomarkers search, lower levels of endogenous metabolite Acetyltryptophan, DL- was identified in the fluid from the affected breasts compared to the control breast fluid.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
The amino acid requirements of man. VIII. The metabolic availability of the optical isomers of acetyltryptophan.
1955 Jan
Patents

Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
Incubation with Acetyltryptophan,DL- resulted in statistically significant inhibition of H2O2-mediated NSC-34 motoneuron cell death. The resulting curve (plotted semi-logarithmically) define the IC50 and maximum protection afforded by acetyltryptophan, DL- (1.0 uM and 22%, respectively).
Substance Class Chemical
Created
by admin
on Sat Dec 16 07:43:56 UTC 2023
Edited
by admin
on Sat Dec 16 07:43:56 UTC 2023
Record UNII
4460NBV53F
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
N-ACETYL-DL-TRYPTOPHAN
Systematic Name English
NSC-49124
Code English
DL-ACETYLTRYPTOPHAN
Common Name English
N-ACETYLTRYPTOPHAN
EP  
Systematic Name English
ACETYLTRYPTOPHAN, DL- [II]
Common Name English
Acetyltryptophan [WHO-DD]
Common Name English
ACETYLTRYPTOPHAN, DL-
II  
Common Name English
N-ACETYLTRYPTOPHAN [EP MONOGRAPH]
Common Name English
ACETYLTRYPTOPHAN
WHO-DD  
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C73539
Created by admin on Sat Dec 16 07:43:57 UTC 2023 , Edited by admin on Sat Dec 16 07:43:57 UTC 2023
Code System Code Type Description
EVMPD
SUB22284
Created by admin on Sat Dec 16 07:43:57 UTC 2023 , Edited by admin on Sat Dec 16 07:43:57 UTC 2023
PRIMARY
CHEBI
70976
Created by admin on Sat Dec 16 07:43:57 UTC 2023 , Edited by admin on Sat Dec 16 07:43:57 UTC 2023
PRIMARY
EVMPD
SUB12165MIG
Created by admin on Sat Dec 16 07:43:57 UTC 2023 , Edited by admin on Sat Dec 16 07:43:57 UTC 2023
PRIMARY
FDA UNII
4460NBV53F
Created by admin on Sat Dec 16 07:43:57 UTC 2023 , Edited by admin on Sat Dec 16 07:43:57 UTC 2023
PRIMARY
ECHA (EC/EINECS)
201-739-3
Created by admin on Sat Dec 16 07:43:57 UTC 2023 , Edited by admin on Sat Dec 16 07:43:57 UTC 2023
PRIMARY
MESH
C006392
Created by admin on Sat Dec 16 07:43:57 UTC 2023 , Edited by admin on Sat Dec 16 07:43:57 UTC 2023
PRIMARY
SMS_ID
100000085832
Created by admin on Sat Dec 16 07:43:57 UTC 2023 , Edited by admin on Sat Dec 16 07:43:57 UTC 2023
PRIMARY
NCI_THESAURUS
C77305
Created by admin on Sat Dec 16 07:43:57 UTC 2023 , Edited by admin on Sat Dec 16 07:43:57 UTC 2023
PRIMARY
RXCUI
1368212
Created by admin on Sat Dec 16 07:43:57 UTC 2023 , Edited by admin on Sat Dec 16 07:43:57 UTC 2023
PRIMARY RxNorm
DAILYMED
4460NBV53F
Created by admin on Sat Dec 16 07:43:57 UTC 2023 , Edited by admin on Sat Dec 16 07:43:57 UTC 2023
PRIMARY
PUBCHEM
2002
Created by admin on Sat Dec 16 07:43:57 UTC 2023 , Edited by admin on Sat Dec 16 07:43:57 UTC 2023
PRIMARY
CAS
87-32-1
Created by admin on Sat Dec 16 07:43:57 UTC 2023 , Edited by admin on Sat Dec 16 07:43:57 UTC 2023
PRIMARY
EPA CompTox
DTXSID40861672
Created by admin on Sat Dec 16 07:43:57 UTC 2023 , Edited by admin on Sat Dec 16 07:43:57 UTC 2023
PRIMARY
NSC
49124
Created by admin on Sat Dec 16 07:43:57 UTC 2023 , Edited by admin on Sat Dec 16 07:43:57 UTC 2023
PRIMARY
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