CERAMIDE NP

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C36H71NO4
Molecular Weight	581.9532
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@H](CO)NC(=O)CCCCCCC\C=C/CCCCCCCC

InChI

InChIKey=ATGQXSBKTQANOH-UWVGARPKSA-N

InChI=1S/C36H71NO4/c1-3-5-7-9-11-13-15-17-18-19-21-23-25-27-29-31-35(40)37-33(32-38)36(41)34(39)30-28-26-24-22-20-16-14-12-10-8-6-4-2/h17-18,33-34,36,38-39,41H,3-16,19-32H2,1-2H3,(H,37,40)/b18-17-/t33-,34+,36-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C36H71NO4
Molecular Weight	581.9532
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	1
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/18717861 | https://www.drugbank.ca/drugs/DB14111 | https://www.ncbi.nlm.nih.gov/pubmed/26206496 | https://www.ncbi.nlm.nih.gov/pubmed/12190621

CERAMIDE NP (previously CERAMIDE 3) is a naturally occurring lipid and major component of the stratum corneum (outer skin layer). Levels of CERAMIDE NP decrease with advancing age. CERAMIDE NP is widely used as a moisturizer in cosmetic products because of its hydrating function. Interactions have been found with ceramide 1, synergistically improving the skin barrier function in humans, i.e. better skin hydration and less transepidermal water loss. There are no safety concerns for cosmetic products containing less than 1% CERAMIDE NP.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
sunburn 4 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=62e138f8-565f-422a-b39f-a1ecd04616da	Inactive ingredient		Approved 8429	NU SKIN AGELOC ME Approved Use Helps prevent sunburn. If used as directed with other sun protection measures, decreases the risk of skin cancer and early skin aging caused by the sun. Launch Date 1.46197434E12

Substance Class	Chemical Created by `admin` on `Sat Dec 16 01:55:19 UTC 2023` Edited by `admin` on `Sat Dec 16 01:55:19 UTC 2023`
Record UNII	4370DF050B
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CERAMIDE 3

Preferred Name

English

CERAMIDE NP

Official Name

English

CYTOMIDE IIIB

Brand Name

English

CYTOMIDE IIIA

Brand Name

English

CERAMIDE III

Brand Name

English

CERAMIDE NP [INCI]

Common Name

English

N-OCTADECANOYLPHYTOSPHINGOSINE

Systematic Name

English

CERAMIDE IIIB

Brand Name

English

OCTADECANAMIDE, N-(1,3,4-TRIHYDROXY-2-OCTADECYL)-

Systematic Name

English

CERAMIDE 3 (RETIRED ) [INCI]

Common Name

English

Code System Code Type Description

PUBCHEM

57378373