MEMOTINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C17H17NO2
Molecular Weight	267.3224
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=C(OCC2=NCCC3=C2C=CC=C3)C=C1

InChI

InChIKey=NOCSCLPQKGWLDB-UHFFFAOYSA-N

InChI=1S/C17H17NO2/c1-19-14-6-8-15(9-7-14)20-12-17-16-5-3-2-4-13(16)10-11-18-17/h2-9H,10-12H2,1H3

HIDE SMILES / InChI

Molecular Formula	C17H17NO2
Molecular Weight	267.3224
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5309492 | https://www.ncbi.nlm.nih.gov/pubmed/4318080

Memotine (UK2371)is an isoquinoline antiviral compound. In vitro, it is active against myxoviruses and paramyxoviruses. It is not active against rhinoviruses. Memotine given orally reduces the antibody response and the incidence of clinical reactions.

Approval Year

PubMed

Title	Date	PubMed
The antiviral activity of isoquinoline drugs for rhinoviruses in vitro and in vivo.	1970-05	4318080
The antiviral activity of the isoquinolines famotine and memotine in respiratory infections in man.	1969	5309492

Sample Use Guides

In Vitro Use Guide

A period of direct contact with a concentration of 20 mug/ml or less of memotine (1-(p-methoxyphenoxymethyl)-3,4-dihydroisoquinoline hydrochloride) inactivates myxoviruses and paramyxoviruses.

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:19:55 GMT 2025` Edited by `admin` on `Mon Mar 31 18:19:55 GMT 2025`
Record UNII	42BHH3WP14
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MEMOTINE

Official Name

English

3,4-DIHYDRO-1-((P-METHOXYPHENOXY)METHYL)ISOQUINOLINE

Preferred Name

English

memotine [INN]

Common Name

English

ISOQUINOLINE, 3,4-DIHYDRO-1-((4-METHOXYPHENOXY)METHYL)-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C281