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Details

Stereochemistry ABSOLUTE
Molecular Formula C23H32O3
Molecular Weight 356.4984
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 6
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of QUINESTRADOL

SMILES

[H][C@@]12C[C@@H](O)[C@H](O)[C@@]1(C)CC[C@]3([H])C4=C(CC[C@@]23[H])C=C(OC5CCCC5)C=C4

InChI

InChIKey=ODYKCPYPRCJXLY-PZORDLPLSA-N
InChI=1S/C23H32O3/c1-23-11-10-18-17-9-7-16(26-15-4-2-3-5-15)12-14(17)6-8-19(18)20(23)13-21(24)22(23)25/h7,9,12,15,18-22,24-25H,2-6,8,10-11,13H2,1H3/t18-,19-,20+,21-,22+,23+/m1/s1

HIDE SMILES / InChI

Molecular Formula C23H32O3
Molecular Weight 356.4984
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 6 / 6
E/Z Centers 0
Optical Activity UNSPECIFIED

Quinestradol is an estrogen derivative patented by Francesco Vismara Societa per Azioni and Alberto Ercol for the treatment of senile vulvovaginitis and related conditions. In preclinical trilals, quinestradol shows feminizing action in rats. A clinical trial of Quinestradol appeared to be justified since there was considerable evidence that the preparation was safe and free from side effects.

Approval Year

PubMed

PubMed

TitleDatePubMed
Temporal relationships between hormone receptor binding and biological responses in the uterus: studies with short- and long-acting derivatives of estriol.
1976 Jan
Biology and receptor interactions of estriol and estriol derivatives in vitro and in vivo.
1984 Apr
Patents

Patents

Sample Use Guides

0.25 mg four times a day.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:28:32 GMT 2023
Edited
by admin
on Fri Dec 15 16:28:32 GMT 2023
Record UNII
422L8173W8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
QUINESTRADOL
INN   MART.   WHO-DD  
INN  
Official Name English
quinestradol [INN]
Common Name English
QUINESTRADOL [MART.]
Common Name English
QUINESTRADIOL [MI]
Common Name English
Quinestradol [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C483
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
Code System Code Type Description
FDA UNII
422L8173W8
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
MESH
C012021
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
INN
1778
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
EPA CompTox
DTXSID30878638
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
RXCUI
35215
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY RxNorm
DRUG CENTRAL
2341
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
ChEMBL
CHEMBL2107004
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
SMS_ID
100000080295
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
NCI_THESAURUS
C76999
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
WIKIPEDIA
Quinestradol
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
PUBCHEM
14626804
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
EVMPD
SUB10210MIG
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
ECHA (EC/EINECS)
214-623-2
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
MERCK INDEX
m912
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY Merck Index
CAS
1169-79-5
Created by admin on Fri Dec 15 16:28:32 GMT 2023 , Edited by admin on Fri Dec 15 16:28:32 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY