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Details

Stereochemistry ABSOLUTE
Molecular Formula C23H32O3
Molecular Weight 356.4984
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 6
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of QUINESTRADOL

SMILES

[H][C@@]12C[C@@H](O)[C@H](O)[C@@]1(C)CC[C@]3([H])C4=C(CC[C@@]23[H])C=C(OC5CCCC5)C=C4

InChI

InChIKey=ODYKCPYPRCJXLY-PZORDLPLSA-N
InChI=1S/C23H32O3/c1-23-11-10-18-17-9-7-16(26-15-4-2-3-5-15)12-14(17)6-8-19(18)20(23)13-21(24)22(23)25/h7,9,12,15,18-22,24-25H,2-6,8,10-11,13H2,1H3/t18-,19-,20+,21-,22+,23+/m1/s1

HIDE SMILES / InChI

Molecular Formula C23H32O3
Molecular Weight 356.4984
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 6 / 6
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Quinestradol is an estrogen derivative patented by Francesco Vismara Societa per Azioni and Alberto Ercol for the treatment of senile vulvovaginitis and related conditions. In preclinical trilals, quinestradol shows feminizing action in rats. A clinical trial of Quinestradol appeared to be justified since there was considerable evidence that the preparation was safe and free from side effects.

Originator

Approval Year

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
0.25 mg four times a day.
Route of Administration: Oral
Substance Class Chemical
Record UNII
422L8173W8
Record Status Validated (UNII)
Record Version