Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H12FN3OS |
| Molecular Weight | 265.307 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NCCNC(=O)C1=C(SC=N1)C2=CC=CC(F)=C2
InChI
InChIKey=SCKBPXUWGMKLDM-UHFFFAOYSA-N
InChI=1S/C12H12FN3OS/c13-9-3-1-2-8(6-9)11-10(16-7-18-11)12(17)15-5-4-14/h1-3,6-7H,4-5,14H2,(H,15,17)
| Molecular Formula | C12H12FN3OS |
| Molecular Weight | 265.307 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Up-regulation of the isoenzymes MAO-A and MAO-B in the human basal ganglia and pons in Huntington's disease revealed by quantitative enzyme radioautography. | 2011-01-25 |
|
| MAO-A-induced mitogenic signaling is mediated by reactive oxygen species, MMP-2, and the sphingolipid pathway. | 2007-07-01 |
|
| Differential substrate specificity of monoamine oxidase in the rat heart and renal cortex. | 2003-07-11 |
|
| Increased density of catalytic sites and expression of brain monoamine oxidase A in humans with hepatic encephalopathy. | 1997-03 |
|
| Molecular neuroanatomy of human monoamine oxidases A and B revealed by quantitative enzyme radioautography and in situ hybridization histochemistry. | 1996-02 |
|
| Increased monoamine oxidase B activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography. | 1994-09 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:52:18 GMT 2025
by
admin
on
Mon Mar 31 19:52:18 GMT 2025
|
| Record UNII |
40Y4916ZJ4
|
| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID10155590
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127500-84-9
Created by
admin on Mon Mar 31 19:52:18 GMT 2025 , Edited by admin on Mon Mar 31 19:52:18 GMT 2025
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40Y4916ZJ4
Created by
admin on Mon Mar 31 19:52:18 GMT 2025 , Edited by admin on Mon Mar 31 19:52:18 GMT 2025
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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TARGET -> INHIBITOR |
BINDING
IC50
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LABELED -> NON-LABELED |
|
![Amine oxidase [flavin-containing] A (Rat)](https://drugs.ncats.io/assets/ginas/images/protein.svg "Amine oxidase [flavin-containing] A (Rat)")
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
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