CYACETACIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C3H5N3O
Molecular Weight	99.0913
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NNC(=O)CC#N

InChI

InChIKey=HPHBOJANXDKUQD-UHFFFAOYSA-N

InChI=1S/C3H5N3O/c4-2-1-3(7)6-5/h1,5H2,(H,6,7)

HIDE SMILES / InChI

Molecular Formula	C3H5N3O
Molecular Weight	99.0913
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.rlsnet.ru/mnn_index_id_1940.htm

Cyacetacide is a biochemical used in the past as an anti-tuberculosis agent and currently used in Russia to for the treatment of various forms of tubercular lesions of the eye: keratitis, scleritis, uveitis, chorioretinitis, tuberculosis-allergic diseases and eye diseases of non-tubercular origin. Cyacetacide has also been used to derive compounds that may have antitumor properties.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Pulmonary tuberculosis 17 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13778907	Curative		Withdrawn	Unknown Approved Use Unknown

PubMed

Title	Date	PubMed
The reaction of cyanoacetylhydrazine with omega-bromo(4-methyl)acetophenone: synthesis of heterocyclic derivatives with antitumor activity.	2010 May 17	20657502

Patents

Sample Use Guides

In Vivo Use Guide

Ciazide is administered orally 0.1 g 3 times a day for a month (total 9.0 g of the drug), and then in combination with other antibacterial drugs.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:32:01 GMT 2023` Edited by `admin` on `Fri Dec 15 16:32:01 GMT 2023`
Record UNII	40H59YCS67
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CYACETACIDE

Official Name

English

CYANOACETIC ACID HYDRAZIDE

Systematic Name

English

cyacetacide [INN]

Common Name

English

CYACETACIDE [HSDB]

Common Name

English

CYACETACIDE [MART.]

Common Name

English

CYACETAZIDE

Common Name

English

NSC-24261

Code

English

CYACETACIDE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C52588