AZIDAMFENICOL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C11H13N5O5
Molecular Weight	295.2514
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of AZIDAMFENICOL

Structure Search

SMILES

OC[C@@H](NC(=O)CN=[N+]=[N-])[C@H](O)C1=CC=C(C=C1)[N+]([O-])=O

InChI

InChIKey=SGRUZFCHLOFYHZ-MWLCHTKSSA-N

InChI=1S/C11H13N5O5/c12-15-13-5-10(18)14-9(6-17)11(19)7-1-3-8(4-2-7)16(20)21/h1-4,9,11,17,19H,5-6H2,(H,14,18)/t9-,11-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C11H13N5O5
Molecular Weight	295.2514
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	1
Optical Activity	UNSPECIFIED

Description
Sources: https://www.toku-e.com/Azidamfenicol-P2999.aspx

Azidamfenicol is a semi-synthetic chloramphenicol in which the nitro moiety is replaced with a methylsulphone and the dichloroacetamide is replaced with azidoacetamide. Azidamfenicol is a broad spectrum antibiotic with good activity against Gram-negative and anaerobic bacteria.

Originator

Approval Year

Sample Use Guides

In Vivo Use Guide

Eye Drops Containing 1% Azidamfenicol

Route of Administration: Topical

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:33:22 GMT 2023` Edited by `admin` on `Fri Dec 15 15:33:22 GMT 2023`
Record UNII	40257685LM
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AZIDAMFENICOL

Official Name

English

AZIDAMFENICOL [MART.]

Common Name

English

AZIDAMFENICOL [MI]

Common Name

English

AZIDOAMFENICOL

Common Name

English

azidamfenicol [INN]

Common Name

English

POSIFENICOL

Brand Name

English

Azidamfenicol [WHO-DD]

Common Name

English

D(-)-THREO-2-AZIDO-N-(.BETA.-HYDROXY-.ALPHA.-(HYDROXYMETHYL)-P-NITROPHENETHYL)ACETAMIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C258

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

WHO-ATC

S01AA25

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

Code System Code Type Description

MERCK INDEX

m1018

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

PRIMARY

Merck Index

INN

1703

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

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FDA UNII

40257685LM

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

PRIMARY

EVMPD

SUB05654MIG

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

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SMS_ID

100000086083

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

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WIKIPEDIA

Azidamfenicol

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

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DRUG CENTRAL

3011

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

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NCI_THESAURUS

C72712

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

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ChEMBL

CHEMBL278788

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

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ECHA (EC/EINECS)

237-552-9

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

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EPA CompTox

DTXSID90160647

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

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DRUG BANK

DB13294

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

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PUBCHEM

62858

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

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CAS

13838-08-9

Created by admin on Fri Dec 15 15:33:23 GMT 2023 , Edited by admin on Fri Dec 15 15:33:23 GMT 2023

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