U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 18:39:34 GMT 2023
Edited
by admin
on Sat Dec 16 18:39:34 GMT 2023
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State LIVE ATTENUATED GENETICALLY MODIFIED
Organism Family Adenoviridae
Organism Genus Mastadenovirus
Infraspecific Type SUBSTRAIN
Infraspecific Name adenovirus serotype 5/35-CVM-LOAd703 (TMZ-CD40L and 4-1BBL)
Part whole
Record UNII
3ZQ57V6YWZ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DELOLIMOGENE MUPADENOREPVEC
INN  
Official Name English
delolimogene mupadenorepvec [INN]
Common Name English
DNA (SYNTHETIC HUMAN ADENOVIRUS 5/35 VECTOR LOAD703 HUMAN CD137 LIGAND AND TRIMERIZED MEMBRANE-BOUND ISOLEUCINE ZIPPER-CONTAINING HUMAN CD40 LIGAND-SPECIFYING)
Common Name English
A CONDITIONALLY REPLICATING ADENOVIRUS SEROTYPE 5/35 GENETICALLY ENGINEERED TO EXPRESS A TRIMERIZED MEMBRANE-BOUND CD40 LIGAND (TMZ-CD40L) AND TUMOR NECROSIS FACTOR SUPERFAMILY MEMBER 9 (TNFSF9, 4-1BBL, CD137), UNDER THE CONTROL OF A CYTOMEGALOVIRUS (CMV
Common Name English
Code System Code Type Description
CAS
2061938-98-3
Created by admin on Sat Dec 16 18:39:34 GMT 2023 , Edited by admin on Sat Dec 16 18:39:34 GMT 2023
PRIMARY
INN
10776
Created by admin on Sat Dec 16 18:39:34 GMT 2023 , Edited by admin on Sat Dec 16 18:39:34 GMT 2023
PRIMARY
NCI_THESAURUS
C148462
Created by admin on Sat Dec 16 18:39:34 GMT 2023 , Edited by admin on Sat Dec 16 18:39:34 GMT 2023
PRIMARY
FDA UNII
3ZQ57V6YWZ
Created by admin on Sat Dec 16 18:39:34 GMT 2023 , Edited by admin on Sat Dec 16 18:39:34 GMT 2023
PRIMARY
Related Record Type Details
EXPRESSED PROTEIN->VECTOR
EXPRESSED PROTEIN->VECTOR
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
GENE_EXPRESSION VECTOR DELOLIMOGENE MUPADENOREPVEC GENOME SEQUENCE WFX2EAM4K8