Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H8O4.2Na |
| Molecular Weight | 190.1049 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].[Na+].[O-]C(=O)CCCCC([O-])=O
InChI
InChIKey=KYKFCSHPTAVNJD-UHFFFAOYSA-L
InChI=1S/C6H10O4.2Na/c7-5(8)3-1-2-4-6(9)10;;/h1-4H2,(H,7,8)(H,9,10);;/q;2*+1/p-2
| Molecular Formula | Na |
| Molecular Weight | 22.98976928 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C6H8O4 |
| Molecular Weight | 144.1253 |
| Charge | -2 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Adipic acid has been incorporated into controlled-release formulation matrix tablets to obtain a pH-independent release for both weakly basic and weakly acidic drugs. It has also been incorporated into the polymeric coating of hydrophilic monolithic systems to modulate the intragel pH, resulting in zero-order release of hydrophilic drugs. The disintegration at intestinal pH of the enteric polymer shellac has been reported to improve when adipic acid was used as a pore-forming agent without affecting release in the acidic media. Adipic acid is used to make bisobrin an antifibrinolytic.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Organic acids in aqueous humour and plasma: post mortem study in infants and diagnosis of enzymopathies. | 1991 |
|
| Characterization of a microorganism isolated from the effluent of hydrogen fermentation by microflora. | 2001 |
|
| Determination of adipate plasticizers in poly(vinyl chloride) by microwave-assisted extraction. | 2002 Jul 19 |
|
| A molecular oyster: a neutral anion receptor containing two cyclopeptide subunits with a remarkable sulfate affinity in aqueous solution. | 2002 Oct 30 |
|
| Identification and fragmentation study of plasticizers with post-source decay matrix-assisted laser desorption/ionization mass spectrometry. | 2003 |
|
| Structural analyses and magnetic properties of 3D coordination polymeric networks of nickel(II) maleate and manganese(II) adipate with the flexible 1,2-bis(4-pyridyl)ethane ligand. | 2003 Apr 21 |
|
| Continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus: Growth yields and morphological characterization. | 2003 Aug 5 |
|
| Air quality model evaluation data for organics. 6. C3-C24 organic acids. | 2003 Feb 1 |
|
| Influence of the adipate and dissolved oxygen concentrations on the beta-lactam production during continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus. | 2003 Jan |
|
| Alicycliphilus denitrificans gen. nov., sp. nov., a cyclohexanol-degrading, nitrate-reducing beta-proteobacterium. | 2003 Jan |
|
| [Effect of teeth protector on dental injuries during general anesthesia]. | 2003 Jan |
|
| Atmospheric pressure mass spectrometry: a new analytical chemical characterization method for dissolved organic matter in rainwater. | 2003 Jan 1 |
|
| In vitro and in vivo evaluation of mucoadhesive microspheres consisting of dextran derivatives and cellulose acetate butyrate. | 2003 Jun 4 |
|
| Human renal organic anion transporter 1-dependent uptake and toxicity of mercuric-thiol conjugates in Madin-Darby canine kidney cells. | 2003 Mar |
|
| Di(2-ethylhexyl) adipate (DEHA) induced developmental toxicity but not antiandrogenic effects in pre- and postnatally exposed Wistar rats. | 2003 Mar-Apr |
|
| Determination of endocrine-disrupting compounds in water samples by on-line solid-phase extraction-programmed-temperature vaporisation-gas chromatography-mass spectrometry. | 2003 May 23 |
|
| Isolation and characterization of poly(butylene succinate-co-butylene adipate)-degrading microorganism. | 2004 |
|
| Conversion of food waste into hydrogen by thermophilic acidogenesis. | 2005 Feb |
|
| X-ray studies on crystalline complexes involving amino acids and peptides. XLII. Adipic acid complexes of L- and DL-arginine and supramolecular association in arginine-dicarboxylic acid complexes. | 2005 Feb |
|
| Cellulose acetate butyrate microcapsules containing dextran ion-exchange resins as self-propelled drug release system. | 2005 Jul |
|
| Tweezing-adsorptive bubble separation. Analytical method for the selective and high enrichment of metalloenzymes. | 2005 Oct 1 |
|
| Enhancement of the Curie temperature by isomerization of diarylethene (DAE) for an organic-inorganic hybrid system: Co4(OH)7(DAE)0.5.3H2O. | 2006 Dec 11 |
|
| X-ray studies of crystalline complexes involving amino acids and peptides. XLIII. Adipic acid complexes of L- and DL-lysine. | 2006 Mar |
|
| Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006 Nov |
|
| [Physical, chemical and biological properties of food modified starches]. | 2007 |
|
| Genome analysis of Minibacterium massiliensis highlights the convergent evolution of water-living bacteria. | 2007 Aug |
|
| Adipic and malonic acid aqueous solutions: surface tensions and saturation vapor pressures. | 2007 Dec 20 |
|
| Fluxome analysis using GC-MS. | 2007 Feb 7 |
|
| The relationship between instability of H2 production and compositions of bacterial communities within a dark fermentation fluidized-bed bioreactor. | 2007 Jul 1 |
|
| Host-guest adaptability within oxothiomolybdenum wheels: structures, studies in solution and DFT calculations. | 2007 Jul 28 |
|
| Magnetic resonance imaging findings of adult-onset glutaric aciduria type I. | 2007 Jun |
|
| Synthesis and characterization of branched polymers from lipase-catalyzed trimethylolpropane copolymerizations. | 2007 Jun |
|
| Exploring lanthanide luminescence in metal-organic frameworks: synthesis, structure, and guest-sensitized luminescence of a mixed europium/terbium-adipate framework and a terbium-adipate framework. | 2007 May 14 |
|
| [(3)H]Adenine is a suitable radioligand for the labeling of G protein-coupled adenine receptors but shows high affinity to bacterial contaminations in buffer solutions. | 2007 Sep |
|
| Diverse entangled metal-organic framework materials incorporating kinked organodiimine and flexible aliphatic dicarboxylate ligands: synthesis, structure, physical properties, and reversible structural reorganization. | 2007 Sep 3 |
|
| Prenatal phenol and phthalate exposures and birth outcomes. | 2008 Aug |
|
| Determination of insulin in innovative formulations by means of LC coupled to fluorescence detection. | 2008 Dec 15 |
|
| Compatibility study of trans-1,4,5,8-tetranitro-1,4,5,8-tetraazadecalin (TNAD) with some energetic components and inert materials. | 2008 Dec 30 |
|
| Ketotifen controlled release from cellulose acetate propionate and cellulose acetate butyrate membranes. | 2008 Feb |
|
| Determination of phthalates and adipate in bottled water by headspace solid-phase microextraction and gas chromatography/mass spectrometry. | 2008 Jan 18 |
|
| Proteomic investigation of amino acid catabolism in the indigenous gut anaerobe Fusobacterium varium. | 2008 Jul |
|
| Development of a liposaccharide-based delivery system and its application to the design of group A streptococcal vaccines. | 2008 Mar 13 |
|
| Release profile comparison and stability of diltiazem-resin microcapsules in sustained release suspensions. | 2008 Mar 20 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:49:28 GMT 2025
by
admin
on
Mon Mar 31 18:49:28 GMT 2025
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| Record UNII |
3XG6T5KYKM
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| Record Status |
Validated (UNII)
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JECFA EVALUATION |
INS-356
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CODEX ALIMENTARIUS (GSFA) |
INS-356
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245-577-1
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ALTERNATIVE | |||
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7486-38-6
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3XG6T5KYKM
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23311-84-4
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NON-SPECIFIC STOICHIOMETRY | |||
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3XG6T5KYKM
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100000090735
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231-293-5
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24073
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SUB29179
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DTXSID1044726
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SODIUM ADIPATE
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| Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
