Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H8O4.2Na |
| Molecular Weight | 190.1049 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].[Na+].[O-]C(=O)CCCCC([O-])=O
InChI
InChIKey=KYKFCSHPTAVNJD-UHFFFAOYSA-L
InChI=1S/C6H10O4.2Na/c7-5(8)3-1-2-4-6(9)10;;/h1-4H2,(H,7,8)(H,9,10);;/q;2*+1/p-2
| Molecular Formula | Na |
| Molecular Weight | 22.98976928 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C6H8O4 |
| Molecular Weight | 144.1253 |
| Charge | -2 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Adipic acid has been incorporated into controlled-release formulation matrix tablets to obtain a pH-independent release for both weakly basic and weakly acidic drugs. It has also been incorporated into the polymeric coating of hydrophilic monolithic systems to modulate the intragel pH, resulting in zero-order release of hydrophilic drugs. The disintegration at intestinal pH of the enteric polymer shellac has been reported to improve when adipic acid was used as a pore-forming agent without affecting release in the acidic media. Adipic acid is used to make bisobrin an antifibrinolytic.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Compatibility study of trans-1,4,5,8-tetranitro-1,4,5,8-tetraazadecalin (TNAD) with some energetic components and inert materials. | 2008-12-30 |
|
| Determination of insulin in innovative formulations by means of LC coupled to fluorescence detection. | 2008-12-15 |
|
| Prenatal phenol and phthalate exposures and birth outcomes. | 2008-08 |
|
| Proteomic investigation of amino acid catabolism in the indigenous gut anaerobe Fusobacterium varium. | 2008-07 |
|
| Chemical modification of zinc hydroxide nitrate and Zn-Al-layered double hydroxide with dicarboxylic acids. | 2008-04-01 |
|
| Release profile comparison and stability of diltiazem-resin microcapsules in sustained release suspensions. | 2008-03-20 |
|
| Development of a liposaccharide-based delivery system and its application to the design of group A streptococcal vaccines. | 2008-03-13 |
|
| Diclofenac sodium loaded-cellulose acetate butyrate: effect of processing variables on microparticles properties, drug release kinetics and ulcerogenic activity. | 2008-02 |
|
| Ketotifen controlled release from cellulose acetate propionate and cellulose acetate butyrate membranes. | 2008-02 |
|
| Determination of phthalates and adipate in bottled water by headspace solid-phase microextraction and gas chromatography/mass spectrometry. | 2008-01-18 |
|
| Preparation and characterization of hydroxyapatite/poly(ethylene adipate) hybrid composites. | 2008 |
|
| Organic acid concentrations in amniotic fluid found in normal and Down syndrome pregnancies. | 2008 |
|
| Adipic and malonic acid aqueous solutions: surface tensions and saturation vapor pressures. | 2007-12-20 |
|
| Diverse entangled metal-organic framework materials incorporating kinked organodiimine and flexible aliphatic dicarboxylate ligands: synthesis, structure, physical properties, and reversible structural reorganization. | 2007-09-03 |
|
| [(3)H]Adenine is a suitable radioligand for the labeling of G protein-coupled adenine receptors but shows high affinity to bacterial contaminations in buffer solutions. | 2007-09 |
|
| Genome analysis of Minibacterium massiliensis highlights the convergent evolution of water-living bacteria. | 2007-08 |
|
| Host-guest adaptability within oxothiomolybdenum wheels: structures, studies in solution and DFT calculations. | 2007-07-28 |
|
| The relationship between instability of H2 production and compositions of bacterial communities within a dark fermentation fluidized-bed bioreactor. | 2007-07-01 |
|
| Magnetic resonance imaging findings of adult-onset glutaric aciduria type I. | 2007-06 |
|
| Synthesis and characterization of branched polymers from lipase-catalyzed trimethylolpropane copolymerizations. | 2007-06 |
|
| Exploring lanthanide luminescence in metal-organic frameworks: synthesis, structure, and guest-sensitized luminescence of a mixed europium/terbium-adipate framework and a terbium-adipate framework. | 2007-05-14 |
|
| Effect of the dispersion of Eudragit S100 powder on the properties of cellulose acetate butyrate microspheres containing theophylline made by the emulsion-solvent evaporation method. | 2007-05 |
|
| Cellulose acetate butyrate-pH/thermosensitive polymer microcapsules containing aminated poly(vinyl alcohol) microspheres for oral administration of DNA. | 2007-04 |
|
| Fluxome analysis using GC-MS. | 2007-02-07 |
|
| A novel multicompartimental system based on aminated poly(vinyl alcohol) microspheres/succinoylated pullulan microspheres for oral delivery of anionic drugs. | 2007-02-07 |
|
| [Physical, chemical and biological properties of food modified starches]. | 2007 |
|
| Molecular model for host–guest interaction of tetraamino-tert-butylthiacalix[4]arene and tetraamino-tert-butylcalix[4]arene receptors with carboxylate and dicarboxylate guests: an ONIOM study. | 2007 |
|
| Enhancement of the Curie temperature by isomerization of diarylethene (DAE) for an organic-inorganic hybrid system: Co4(OH)7(DAE)0.5.3H2O. | 2006-12-11 |
|
| Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006-11 |
|
| Facile preparation of biodegradable chitosan derivative having poly(butylene glycol adipate) side chains. | 2006-08-15 |
|
| Changes in bacterial community during fermentative hydrogen and acid production from organic waste by thermophilic anaerobic microflora. | 2006-08 |
|
| Ala-504 is a determinant of substrate binding affinity in the mouse Na(+)/dicarboxylate cotransporter. | 2006-06 |
|
| Modulatory effects of chitosan adipate on the T and B lymphocyte subsets in mice. | 2006-06 |
|
| Porous structures of polymer films prepared by spin coating with mixed solvents under humid condition. | 2006-05-09 |
|
| Modelling calcium carbonate biomineralisation processes. | 2006-05 |
|
| Crystal engineering of analogous and homologous organic compounds: hydrogen bonding patterns in trimethoprim hydrogen phthalate and trimethoprim hydrogen adipate. | 2006-04-07 |
|
| X-ray studies of crystalline complexes involving amino acids and peptides. XLIII. Adipic acid complexes of L- and DL-lysine. | 2006-03 |
|
| Amended final report of the safety assessment of dibutyl adipate as used in cosmetics. | 2006 |
|
| Matrix-assisted laser desorption/ionization time-of-flight/time-of-flight tandem mass spectra of poly(butylene adipate). | 2006 |
|
| catena-Poly[[mu-hexanedioato-1kappaO1:2kappaO6-bis[aqua(5-carboxypentanoato-kappaO)copper(II)]]-di-mu-4,4'-bipyridine-1kappaN:1'kappaN';2kappaN:2'kappaN']. | 2005-12 |
|
| Tweezing-adsorptive bubble separation. Analytical method for the selective and high enrichment of metalloenzymes. | 2005-10-01 |
|
| Increased biological hydrogen production with reduced organic loading. | 2005-10 |
|
| Uniaxial drawing of poly[(R)-3-hydroxybutyrate]/cellulose acetate butyrate blends and their orientation behavior. | 2005-09-16 |
|
| catena-Poly[[diaquabis(5-carboxypentanoato-kappaO)cobalt(II)]-mu-1,2-di-4-pyridylethane-kappa2N:N']. | 2005-09 |
|
| Production of 1,3-Propanediol by Clostridium butyricum VPI 3266 in continuous cultures with high yield and productivity. | 2005-09 |
|
| Clinic blood pressure responses to two amlodipine salt formulations, adipate and besylate, in adult Korean patients with mild to moderate hypertension: a multicenter, randomized, double-blind, parallel-group, 8-week comparison. | 2005-06 |
|
| Preparation and in vitro evaluation of propylthiouracil microspheres made of Eudragit RL 100 and cellulose acetate butyrate polymers using the emulsion-solvent evaporation method. | 2005-05 |
|
| Isolation and characterization of poly(butylene succinate-co-butylene adipate)-degrading microorganism. | 2004 |
|
| Characterization of a microorganism isolated from the effluent of hydrogen fermentation by microflora. | 2001 |
|
| Organic acids in aqueous humour and plasma: post mortem study in infants and diagnosis of enzymopathies. | 1991 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:49:28 GMT 2025
by
admin
on
Mon Mar 31 18:49:28 GMT 2025
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| Record UNII |
3XG6T5KYKM
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| Record Status |
Validated (UNII)
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| Record Version |
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JECFA EVALUATION |
INS-356
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CODEX ALIMENTARIUS (GSFA) |
INS-356
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| Code System | Code | Type | Description | ||
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245-577-1
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ALTERNATIVE | |||
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7486-38-6
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3XG6T5KYKM
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23311-84-4
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NON-SPECIFIC STOICHIOMETRY | |||
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3XG6T5KYKM
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100000090735
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231-293-5
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24073
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SUB29179
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DTXSID1044726
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SODIUM ADIPATE
Created by
admin on Mon Mar 31 18:49:28 GMT 2025 , Edited by admin on Mon Mar 31 18:49:28 GMT 2025
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| Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
