CUPRIC SALICYLATE TETRAHYDRATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C7H5O3.Cu.4H2O
Molecular Weight	409.833
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CUPRIC SALICYLATE TETRAHYDRATE

Structure Search

SMILES

O.O.O.O.[Cu++].OC1=CC=CC=C1C([O-])=O.OC2=CC=CC=C2C([O-])=O

InChI

InChIKey=IMGUOQFRYIAXGF-UHFFFAOYSA-L

InChI=1S/2C7H6O3.Cu.4H2O/c2*8-6-4-2-1-3-5(6)7(9)10;;;;;/h2*1-4,8H,(H,9,10);;4*1H2/q;;+2;;;;/p-2

HIDE SMILES / InChI

Molecular Formula	C7H6O3
Molecular Weight	138.1207
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Cu
Molecular Weight	63.546
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/367963

Cupric salicylate is an anti-inflammatory agent which was used as pain relief for patients with osteoarthritis, rheumatoid and other degenerative diseases (as a copper-salicylate complex). The preparation seem to be discontinued for now.

CNS Activity

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Rheumatic diseases 30 Sources: https://www.ncbi.nlm.nih.gov/pubmed/367963	Palliative		Approved 8429	PERMALON Approved Use Unknown

PubMed

Title	Date	PubMed
Copper salicylate as an anti-inflammatory and analgesic agent in arthritic rats.	1983 Feb 28	6600809

Patents

Sample Use Guides

In Vivo Use Guide

Cupric salicylate gel (1.5 g) was applied twice daily to the forearm for four weeks. Cupric salicylate also was given as 6 and 8 intravenous infusions (60-80 mg of copper, Permalon preparation) every 3-4 days.

Route of Administration: Other

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 03:19:08 GMT 2023` Edited by `admin` on `Sat Dec 16 03:19:08 GMT 2023`
Record UNII	3NAB6I41LP
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CUPRIC SALICYLATE TETRAHYDRATE

Common Name

English

COPPER, BIS(SALICYLATO)-, TETRAHYDRATE

Common Name

English

BENZOIC ACID, 2-HYDROXY-, COPPER(2+) SALT (2:1), TETRAHYDRATE

Common Name

English

COPPER, BIS(2-(HYDROXY-.KAPPA.O)BENZOATO-.KAPPA.O)-, TETRAHYDRATE

Common Name

English

CUPRIC SALICYLATE TETRAHYDRATE [MI]

Common Name

English

Code System Code Type Description

FDA UNII

3NAB6I41LP