U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C15H21NO2.ClH
Molecular Weight 283.794
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 4-(2-HYDROXY-3-ISOPROPYLAMINOPROPOXY)INDENE HYDROCHLORIDE

SMILES

Cl.CC(C)NCC(O)COC1=C2C=CCC2=CC=C1

InChI

InChIKey=LQUALIUFEGJTKA-UHFFFAOYSA-N
InChI=1S/C15H21NO2.ClH/c1-11(2)16-9-13(17)10-18-15-8-4-6-12-5-3-7-14(12)15;/h3-4,6-8,11,13,16-17H,5,9-10H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula C15H21NO2
Molecular Weight 247.3327
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Indenolol hydrochloride is a nonselective beta-adrenoceptor antagonist. It is antihypertensive, antiarrhytmic, antianginal drug. It vasodilated forearm arterioles and this effect was antagonized by beta-blockade, thus demonstrating vascular intrinsic sympathomimetic activity. Indenol is able to inhibit an exercise-induced rise in systolic pressure. Indenolol would be able to decrease myocardial O2 consumption.

Approval Year

PubMed

PubMed

TitleDatePubMed
Chiral separation of beta-adrenergic blockers on CelluCoat column by HPLC.
2009 Apr 30
Patents

Sample Use Guides

Single dose - 60 mg
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:58:45 GMT 2023
Edited
by admin
on Fri Dec 15 18:58:45 GMT 2023
Record UNII
3MK6CS750V
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
4-(2-HYDROXY-3-ISOPROPYLAMINOPROPOXY)INDENE HYDROCHLORIDE
Systematic Name English
2-PROPANOL, 1-(1H-INDEN-4-YLOXY)-3-((1-METHYLETHYL)AMINO)-, HYDROCHLORIDE
Systematic Name English
4-(2-HYDROXY-3-ISOPROPYLAMINOPROPOXY)INDENE HCL
Common Name English
2-PROPANOL, 1-(1H-INDEN-4-YLOXY)-3-((1-METHYLETHYL)AMINO)-, HYDROCHLORIDE (1:1)
Systematic Name English
DL-1-(7-INDENYLOXY)-3-ISOPROPYLAMINOPROPANE-2-OL HYDROCHLORIDE
Common Name English
Code System Code Type Description
CAS
59527-63-8
Created by admin on Fri Dec 15 18:58:45 GMT 2023 , Edited by admin on Fri Dec 15 18:58:45 GMT 2023
PRIMARY
PUBCHEM
118333
Created by admin on Fri Dec 15 18:58:45 GMT 2023 , Edited by admin on Fri Dec 15 18:58:45 GMT 2023
PRIMARY
FDA UNII
3MK6CS750V
Created by admin on Fri Dec 15 18:58:45 GMT 2023 , Edited by admin on Fri Dec 15 18:58:45 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE