4-(2-HYDROXY-3-ISOPROPYLAMINOPROPOXY)INDENE

Possibly Marketed Outside US

Details

Stereochemistry	RACEMIC
Molecular Formula	C15H21NO2
Molecular Weight	247.3327
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 4-(2-HYDROXY-3-ISOPROPYLAMINOPROPOXY)INDENE

Structure Search

SMILES

CC(C)NCC(O)COC1=C2C=CCC2=CC=C1

InChI

InChIKey=MPGBPFMOOXKQRX-UHFFFAOYSA-N

InChI=1S/C15H21NO2/c1-11(2)16-9-13(17)10-18-15-8-4-6-12-5-3-7-14(12)15/h3-4,6-8,11,13,16-17H,5,9-10H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C15H21NO2
Molecular Weight	247.3327
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2573443 | https://www.drugfuture.com/chemdata/Indenolol.html | https://www.ncbi.nlm.nih.gov/pubmed/2866966

Indenolol hydrochloride is a nonselective beta-adrenoceptor antagonist. It is antihypertensive, antiarrhytmic, antianginal drug. It vasodilated forearm arterioles and this effect was antagonized by beta-blockade, thus demonstrating vascular intrinsic sympathomimetic activity. Indenol is able to inhibit an exercise-induced rise in systolic pressure. Indenolol would be able to decrease myocardial O2 consumption.

Approval Year

PubMed

Title	Date	PubMed
Chiral separation of beta-adrenergic blockers on CelluCoat column by HPLC.	2009 Apr 30	19203609

Patents

Sample Use Guides

In Vivo Use Guide

Single dose - 60 mg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:56:43 UTC 2023` Edited by `admin` on `Fri Dec 15 15:56:43 UTC 2023`
Record UNII	8GU15N96I8
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

4-(2-HYDROXY-3-ISOPROPYLAMINOPROPOXY)INDENE

Systematic Name

English

2-PROPANOL, 1-(1H-INDEN-4-YLOXY)-3-((1-METHYLETHYL)AMINO)-

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID70866817