BEZITRAMIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C31H32N4O2
Molecular Weight	492.6114
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of BEZITRAMIDE

Structure Search

SMILES

CCC(=O)N1C(=O)N(C2CCN(CCC(C#N)(C3=CC=CC=C3)C4=CC=CC=C4)CC2)C5=C1C=CC=C5

InChI

InChIKey=FLKWNFFCSSJANB-UHFFFAOYSA-N

InChI=1S/C31H32N4O2/c1-2-29(36)35-28-16-10-9-15-27(28)34(30(35)37)26-17-20-33(21-18-26)22-19-31(23-32,24-11-5-3-6-12-24)25-13-7-4-8-14-25/h3-16,26H,2,17-22H2,1H3

HIDE SMILES / InChI

Molecular Formula	C31H32N4O2
Molecular Weight	492.6114
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9414621 | https://www.ncbi.nlm.nih.gov/pubmed/6519169

Bezitramide was developed as an orally long-acting analgesic compound and was marketed under the brand name Burgodin. The overdose of this drug caused death that is why it was withdrawn from the market.

Originator

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
pain 5 Sources: https://www.ncbi.nlm.nih.gov/pubmed/4913411	Primary		Withdrawn	Burgodin Approved Use Unknown

PubMed

PubMed

Title	Date	PubMed

Patents

Patents

Sample Use Guides

In Vivo Use Guide

5 mg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:07:12 UTC 2023` Edited by `admin` on `Sat Dec 16 16:07:12 UTC 2023`
Record UNII	3KXW0Y310I
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BEZITRAMIDE

Official Name

English

BEZITRAMIDE [MI]

Common Name

English

BEZITRAMIDE [MART.]

Common Name

English

BURGODIN

Brand Name

English

R-4845

Code

English

IDS-NB-007

Code

English

Bezitramide [WHO-DD]

Common Name

English

bezitramide [INN]

Common Name

English

N02AC05

Code

English

1-(3-CYANO-3,3-DIPHENYLPROPYL)-4-(2-OXO-3-PROPIONYL-1-BENZIMIDAZOLINYL)PIPERIDINE

Systematic Name

English

R 4845

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C241

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

WHO-VATC

QN02AC05

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

WHO-ATC

N02AC05

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

DEA NO.

9800

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

Code System Code Type Description

ChEMBL

CHEMBL2104149

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

PRIMARY

DRUG BANK

DB01459

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

PRIMARY

MERCK INDEX

m2470

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

PRIMARY

Merck Index

ECHA (EC/EINECS)

239-335-4

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

PRIMARY

WIKIPEDIA

BEZITRAMIDE

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

PRIMARY

FDA UNII

3KXW0Y310I

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

PRIMARY

NCI_THESAURUS

C72109

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

PRIMARY

SMS_ID

100000085875

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

PRIMARY

EPA CompTox

DTXSID90165197

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

PRIMARY

CAS

15301-48-1

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

PRIMARY

INN

1942

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

PRIMARY

DRUG CENTRAL

363

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

PRIMARY

EVMPD

SUB05811MIG

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

PRIMARY

PUBCHEM

61791

Created by admin on Sat Dec 16 16:07:12 UTC 2023 , Edited by admin on Sat Dec 16 16:07:12 UTC 2023

PRIMARY

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