TETRABARBITAL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C12H20N2O3
Molecular Weight	240.2988
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TETRABARBITAL

Structure Search

SMILES

CCCC(CC)C1(CC)C(=O)NC(=O)NC1=O

InChI

InChIKey=ZLUNGGZJSQDFPH-UHFFFAOYSA-N

InChI=1S/C12H20N2O3/c1-4-7-8(5-2)12(6-3)9(15)13-11(17)14-10(12)16/h8H,4-7H2,1-3H3,(H2,13,14,15,16,17)

HIDE SMILES / InChI

Molecular Formula	C12H20N2O3
Molecular Weight	240.2988
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/13603366

Tetrabarbital is a barbituric acid derivative patented by Eli Lilly and Co. as a central nervous system depressant. In chloralosed dogs, intravenous Tetrabarbital 2.5-10 mg/kg, accelerated the heartbeat and lowered the carotid pressure.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Pharmacodynamic study of two barbituric acid derivatives: tetrabarbital and tetrathiobarbital].	1958	13603366

Patents

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:42:08 GMT 2023` Edited by `admin` on `Fri Dec 15 15:42:08 GMT 2023`
Record UNII	3K441526FO
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TETRABARBITAL

Official Name

English

tetrabarbital [INN]

Common Name

English

TETRABARBITAL [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C67084

Created by admin on Fri Dec 15 15:42:08 GMT 2023 , Edited by admin on Fri Dec 15 15:42:08 GMT 2023

Code System Code Type Description

EPA CompTox

DTXSID50861623

Created by admin on Fri Dec 15 15:42:08 GMT 2023 , Edited by admin on Fri Dec 15 15:42:08 GMT 2023

PRIMARY

CAS

76-23-3

Created by admin on Fri Dec 15 15:42:08 GMT 2023 , Edited by admin on Fri Dec 15 15:42:08 GMT 2023

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INN

364

Created by admin on Fri Dec 15 15:42:08 GMT 2023 , Edited by admin on Fri Dec 15 15:42:08 GMT 2023

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EVMPD

SUB10938MIG

Created by admin on Fri Dec 15 15:42:08 GMT 2023 , Edited by admin on Fri Dec 15 15:42:08 GMT 2023

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ECHA (EC/EINECS)

200-946-6

Created by admin on Fri Dec 15 15:42:08 GMT 2023 , Edited by admin on Fri Dec 15 15:42:08 GMT 2023

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FDA UNII

3K441526FO

Created by admin on Fri Dec 15 15:42:08 GMT 2023 , Edited by admin on Fri Dec 15 15:42:08 GMT 2023

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MERCK INDEX

m957

Created by admin on Fri Dec 15 15:42:08 GMT 2023 , Edited by admin on Fri Dec 15 15:42:08 GMT 2023

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Merck Index

WIKIPEDIA

Tetrabarbital

Created by admin on Fri Dec 15 15:42:08 GMT 2023 , Edited by admin on Fri Dec 15 15:42:08 GMT 2023

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NCI_THESAURUS

C74383

Created by admin on Fri Dec 15 15:42:08 GMT 2023 , Edited by admin on Fri Dec 15 15:42:08 GMT 2023

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PUBCHEM

101534

Created by admin on Fri Dec 15 15:42:08 GMT 2023 , Edited by admin on Fri Dec 15 15:42:08 GMT 2023

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SMS_ID

100000082716

Created by admin on Fri Dec 15 15:42:08 GMT 2023 , Edited by admin on Fri Dec 15 15:42:08 GMT 2023

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ChEMBL

CHEMBL2107053

Created by admin on Fri Dec 15 15:42:08 GMT 2023 , Edited by admin on Fri Dec 15 15:42:08 GMT 2023

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DRUG CENTRAL

3840

Created by admin on Fri Dec 15 15:42:08 GMT 2023 , Edited by admin on Fri Dec 15 15:42:08 GMT 2023

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Related Record Type Details


					3K441526FO

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