Efclarofusp alfa

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 10:35:46 GMT 2025` Edited by `admin` on `Wed Apr 02 10:35:46 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	Human/Calloselasma rhodostoma
Sequence Type	COMPLETE
Record UNII	3E9XUG7SWS
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Vascular endothelial growth factor receptor 1 (human extracellular immunoglobulin domain 2 fragment) fusion protein with vascular endothelial growth factor receptor 2 (human extracellular immunoglobulin domain 3 fragment) fusion protein with immunoglobul

Preferred Name

English

Efclarofusp alfa

Common Name

English

human vascular endothelial growth factor receptor 1 (VEGFR1, vascular permeability factor receptor, Fms-like tyrosine kinase 1, FLT1, tyrosine-protein kinase receptor FLT, tyrosine-protein kinase FRT, EC:2.7.10.1), fragment 103-206 (containing the Ig-lik

Common Name

English

efclarofusp alfa [INN]

Common Name

English

Code System Code Type Description

FDA UNII

3E9XUG7SWS

Created by admin on Wed Apr 02 10:35:46 GMT 2025 , Edited by admin on Wed Apr 02 10:35:46 GMT 2025

PRIMARY

INN

13543

Created by admin on Wed Apr 02 10:35:46 GMT 2025 , Edited by admin on Wed Apr 02 10:35:46 GMT 2025

PRIMARY

CAS

3053638-35-7

Created by admin on Wed Apr 02 10:35:46 GMT 2025 , Edited by admin on Wed Apr 02 10:35:46 GMT 2025

PRIMARY

From	To
2_452	2_460
2_352	2_410
2_246	2_306
2_124	2_185
2_30	2_79
1_452	1_460
1_352	1_410
1_246	1_306
1_214	2_214
1_211	2_211
1_124	1_185
1_30	1_79

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_36
N	1_68
N	1_123
N	1_196
N	1_282
N	2_36
N	2_68
N	2_123
N	2_196
N	2_282

Related Record Type Details


					3E9XUG7SWS

Efclarofusp alfa

ACTIVE MOIETY

Comments:

angiogenesis inhibitor

Interaction Type:

PRECLINICAL

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL