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Details

Stereochemistry ABSOLUTE
Molecular Formula C13H25N4O2.OTc
Molecular Weight 384.2689
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 2
Charge 0

SHOW SMILES / InChI
Structure of TECHNETIUM TC-99M EXAMETAZIME

SMILES

O=[99Tc+3].C[C@@H]([N-]CC(C)(C)C[N-][C@H](C)C(\C)=N\[O-])C(\C)=N\O

InChI

InChIKey=ZLRVWFDVJWKAIL-LXMACRGBSA-M
InChI=1S/C13H26N4O2.O.Tc/c1-9(11(3)16-18)14-7-13(5,6)8-15-10(2)12(4)17-19;;/h9-10,18-19H,7-8H2,1-6H3;;/q-2;;+3/p-1/b16-11+,17-12+;;/t9-,10-;;/m1../s1/i;;1+1

HIDE SMILES / InChI
Molecular Formula C13H26N4O2
Molecular Weight 270.3711
Charge -2
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 2
Optical Activity UNSPECIFIED
Molecular Formula OTc
Molecular Weight 114.9057
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

1973
98
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Approved
8429
OSTEOLITE

Approved Use

Unknown

Launch Date

2.50992001E11
Diagnostic
Approved
8429
DRAXIMAGE MDP-10

Approved Use

MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis.

Launch Date

2.80972788E11
PubMed

PubMed

TitleDatePubMed
Future of low specific activity molybdenum-99/technetium-99m generator.
2012 Oct
Patents

Patents

20050082469
43

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:54:41 UTC 2023
Edited
by admin
on Fri Dec 15 15:54:41 UTC 2023
Record UNII
3B744AG22N
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
TECHNETIUM TC-99M EXAMETAZIME
Common Name English
TECHNETIUM (99MTC) EXAMETAZIME
Common Name English
TECHNETIUM TC 99M EXAMETAZIME [USAN]
Common Name English
TC-99M HMPAO
Common Name English
Technetium tc 99m exametazime [WHO-DD]
Common Name English
TECHNETIUM TC 99M EXAMETAZIME
USAN   WHO-DD  
USAN  
Official Name English
Classification Tree Code System Code
WHO-VATC QV09AA01
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
NCI_THESAURUS C2124
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
WHO-ATC V09AA01
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
NDF-RT N0000177914
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
NDF-RT N0000000205
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
Code System Code Type Description
FDA UNII
3B744AG22N
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
PRIMARY
DRUG BANK
DB09163
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
PRIMARY
CAS
100504-35-6
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
ALTERNATIVE
ChEMBL
CHEMBL2111018
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
PRIMARY
PUBCHEM
11954234
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
PRIMARY
NCI_THESAURUS
C87402
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
PRIMARY
EVMPD
SUB15467MIG
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
PRIMARY
DRUG CENTRAL
3887
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
PRIMARY
DAILYMED
3B744AG22N
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
PRIMARY
RXCUI
1431726
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
PRIMARY RxNorm
CAS
99944-78-2
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
PRIMARY
WIKIPEDIA
Technetium (99mTc) exametazime
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
PRIMARY
SMS_ID
100000092172
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
PRIMARY
LACTMED
Technetium Tc 99m Exametazime
Created by admin on Fri Dec 15 15:54:41 UTC 2023 , Edited by admin on Fri Dec 15 15:54:41 UTC 2023
PRIMARY
Related Record Type Details
TECHNETIUM TC-99M EXAMETAZIME KIT
SUB_CONCEPT->SUBSTANCE
Structure of EXAMETAZIME
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of TECHNETIUM TC-99M EXAMETAZIME
ACTIVE MOIETY
Structure of TECHNETIUM TC-99M
ACTIVE MOIETY
NIH
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