TECHNETIUM TC-99M EXAMETAZIME

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C13H25N4O2.OTc
Molecular Weight	384.2689
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure of TECHNETIUM TC-99M EXAMETAZIME

Structure Search

SMILES

O=[99Tc+3].C[C@@H]([N-]CC(C)(C)C[N-][C@H](C)C(\C)=N\[O-])C(\C)=N\O

InChI

InChIKey=ZLRVWFDVJWKAIL-LXMACRGBSA-M

InChI=1S/C13H26N4O2.O.Tc/c1-9(11(3)16-18)14-7-13(5,6)8-15-10(2)12(4)17-19;;/h9-10,18-19H,7-8H2,1-6H3;;/q-2;;+3/p-1/b16-11+,17-12+;;/t9-,10-;;/m1../s1/i;;1+1

HIDE SMILES / InChI

Molecular Formula	C13H26N4O2
Molecular Weight	270.3711
Charge	-2
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	2
Optical Activity	UNSPECIFIED

Molecular Formula	OTc
Molecular Weight	114.9057
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.hindawi.com/journals/stni/2014/839369/
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2554
bone problems 43 Sources: https://www.drugs.com/cons/osteolite.html	Diagnostic	Approved 8307	OSTEOLITE Approved Use Unknown Launch Date 2.50992001E11
osteogenesis 43 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018035s032lbl.pdf	Diagnostic	Approved 8307	DRAXIMAGE MDP-10 Approved Use MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis. Launch Date 2.80972788E11

PubMed

Title	Date	PubMed
Future of low specific activity molybdenum-99/technetium-99m generator.	2012 Oct	22642420

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 16 18:35:52 UTC 2022` Edited by `admin` on `Fri Dec 16 18:35:52 UTC 2022`
Record UNII	3B744AG22N
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

TECHNETIUM TC-99M EXAMETAZIME

Common Name

English

TECHNETIUM (99MTC) EXAMETAZIME

Common Name

English

TECHNETIUM TC 99M EXAMETAZIME [USAN]

Common Name

English

TC-99M HMPAO

Common Name

English

Technetium tc 99m exametazime [WHO-DD]

Common Name

English

TECHNETIUM TC 99M EXAMETAZIME

Official Name

English

Classification Tree Code System Code

WHO-VATC

QV09AA01