AZD-3965

Investigational

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H24F3N5O5S
Molecular Weight	515.506
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)N1C2=C(C(C(=O)N3C[C@](C)(O)CO3)=C(CC4=C(C)NN=C4C(F)(F)F)S2)C(=O)N(C)C1=O

InChI

InChIKey=PRNXOFBDXNTIFG-FQEVSTJZSA-N

InChI=1S/C21H24F3N5O5S/c1-9(2)29-18-14(16(30)27(5)19(29)32)13(17(31)28-7-20(4,33)8-34-28)12(35-18)6-11-10(3)25-26-15(11)21(22,23)24/h9,33H,6-8H2,1-5H3,(H,25,26)/t20-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C21H24F3N5O5S
Molecular Weight	515.506
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Monocarboxylate transporter 1 2 Target ID: CHEMBL4360 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25281618	Inhibitor 8297		0.14 nM [EC50]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 14:29:11 GMT 2023` Edited by `admin` on `Sat Dec 16 14:29:11 GMT 2023`
Record UNII	39OM5Y4K2F
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AZD-3965

Code

English

AZD 3965 [WHO-DD]

Common Name

English

AZD3965

Common Name

English

THIENO(2,3-D)PYRIMIDINE-2,4(1H,3H)-DIONE, 5-(((4S)-4-HYDROXY-4-METHYL-2-ISOXAZOLIDINYL)CARBONYL)-3-METHYL-1-(1-METHYLETHYL)-6-((5-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-4-YL)METHYL)-

Systematic Name

English

5-(((4S)-4-HYDROXY-4-METHYL-2-ISOXAZOLIDINYL)CARBONYL)-3-METHYL-1-(1-METHYLETHYL)-6-((5-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-4-YL)METHYL)THIENO(2,3-D)PYRIMIDINE-2,4(1H,3H)-DIONE

Systematic Name

English

Code System Code Type Description

CAS

1448671-31-5