Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C10H14N2O6 |
Molecular Weight | 258.228 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=CC(=O)NC2=O
InChI
InChIKey=SXUXMRMBWZCMEN-ZOQUXTDFSA-N
InChI=1S/C10H14N2O6/c1-17-8-7(15)5(4-13)18-9(8)12-3-2-6(14)11-10(12)16/h2-3,5,7-9,13,15H,4H2,1H3,(H,11,14,16)/t5-,7-,8-,9-/m1/s1
Molecular Formula | C10H14N2O6 |
Molecular Weight | 258.228 |
Charge | 0 |
Count |
|
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 4 / 4 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: 2'-O-methyluridine hydrolase (E. coli) Sources: https://www.ncbi.nlm.nih.gov/pubmed/30405065 |
PubMed
Title | Date | PubMed |
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Single methylation of 23S rRNA triggers late steps of 50S ribosomal subunit assembly. | 2015 Aug 25 |
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A novel nucleoside hydrolase from Lactobacillus buchneri LBK78 catalyzing hydrolysis of 2'-O-methylribonucleosides. | 2016 Aug |
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ADME studies of [5-(3)H]-2'-O-methyluridine nucleoside in mice: a building block in siRNA therapeutics. | 2016 Feb |
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Enzymatic synthesis of 2'-O-methylribonucleosides with a nucleoside hydrolase family enzyme from Lactobacillus buchneri LBK78. | 2017 Jun |
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Osmium Tag for Post-transcriptionally Modified RNA. | 2018 Aug 6 |
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New nucleoside hydrolase with transribosylation activity from Agromyces sp. MM-1 and its application for enzymatic synthesis of 2'-O-methylribonucleosides. | 2018 Jan |
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Identification of a 2'-O-Methyluridine Nucleoside Hydrolase Using the Metagenomic Libraries. | 2018 Nov 7 |
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Structural and Energetic Effects of O2'-Ribose Methylation of Protonated Pyrimidine Nucleosides. | 2019 Nov |
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Distinct Modified Nucleosides in tRNA(Trp) from the Hyperthermophilic Archaeon Thermococcus kodakarensis and Requirement of tRNA m(2)G10/m(2)(2)G10 Methyltransferase (Archaeal Trm11) for Survival at High Temperatures. | 2019 Nov 1 |
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 10:29:28 GMT 2023
by
admin
on
Sat Dec 16 10:29:28 GMT 2023
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Record UNII |
399VZB6TMB
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Record Status |
Validated (UNII)
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Record Version |
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