Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H23FN4O8 |
| Molecular Weight | 441.3989 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C(CCN=C(c1ccc(F)nc1)O)C[C@@]([H])(C(=O)O)N=C(N[C@@]([H])(CCC(=O)O)C(=O)O)O
InChI
InChIKey=OLWVRJUNLXQDSP-MVBOSPHXSA-N
InChI=1S/C18H23FN4O8/c19-13-6-4-10(9-21-13)15(26)20-8-2-1-3-11(16(27)28)22-18(31)23-12(17(29)30)5-7-14(24)25/h4,6,9,11-12H,1-3,5,7-8H2,(H,20,26)(H,24,25)(H,27,28)(H,29,30)(H2,22,23,31)/t11-,12-/m0/s1/i19-1
| Molecular Formula | C18H23FN4O8 |
| Molecular Weight | 441.3989 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
DCFPYL F-18 is an urea-based radiotracer composed of the prostate-specific membrane antigen (PSMA)-targeting agent DCFPyL and labeled with the positron-emitting isotope, fluorine F 18, that can potentially be used for positron-emitting tomography (PET) imaging. Upon administration of fluorine F 18 DCFPyL, the DCFPyL moiety binds to PSMA expressed on tumor cells. The fluorine F 18 moiety facilitates PET imaging of PSMA-expressing tumor cells. DCFPYL F-18 is investigated in a number of clinical trials in patients with prostate cancer and neuroendocrine tumors.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Jun 25 21:29:12 UTC 2021
by
admin
on
Fri Jun 25 21:29:12 UTC 2021
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| Record UNII |
3934EF02T7
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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3934EF02T7
Created by
admin on Fri Jun 25 21:29:12 UTC 2021 , Edited by admin on Fri Jun 25 21:29:12 UTC 2021
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DB14805
Created by
admin on Fri Jun 25 21:29:12 UTC 2021 , Edited by admin on Fri Jun 25 21:29:12 UTC 2021
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SUB189818
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admin on Fri Jun 25 21:29:12 UTC 2021 , Edited by admin on Fri Jun 25 21:29:12 UTC 2021
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1207181-29-0
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admin on Fri Jun 25 21:29:12 UTC 2021 , Edited by admin on Fri Jun 25 21:29:12 UTC 2021
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52950901
Created by
admin on Fri Jun 25 21:29:12 UTC 2021 , Edited by admin on Fri Jun 25 21:29:12 UTC 2021
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