CRA-1000

Details

Stereochemistry	ACHIRAL
Molecular Formula	C28H33FN4S
Molecular Weight	476.652
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN(C1=NC(C)=CC(=N1)N2CCC(=CC2)C3=CC=CC(F)=C3)C4=CC=C(C=C4SC)C(C)C

InChI

InChIKey=DDSMCPASYQDKFS-UHFFFAOYSA-N

InChI=1S/C28H33FN4S/c1-6-33(25-11-10-22(19(2)3)18-26(25)34-5)28-30-20(4)16-27(31-28)32-14-12-21(13-15-32)23-8-7-9-24(29)17-23/h7-12,16-19H,6,13-15H2,1-5H3

HIDE SMILES / InChI

Molecular Formula	C28H33FN4S
Molecular Weight	476.652
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
In vitro pharmacological profile of nonpeptide CRF1 receptor antagonists, CRA1000 and CRA1001.	1999 Apr 29	10357258
Corticotropin-releasing factor receptor type 1 is involved in the stress-induced exacerbation of chronic contact dermatitis in rats.	2003 Feb	12631246

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:21:41 GMT 2023` Edited by `admin` on `Sat Dec 16 08:21:41 GMT 2023`
Record UNII	3899V9A17F
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CRA-1000

Common Name

English

2-PYRIMIDINAMINE, N-ETHYL-4-(4-(3-FLUOROPHENYL)-3,6-DIHYDRO-1(2H)-PYRIDINYL)-6-METHYL-N-(4-(1-METHYLETHYL)-2-(METHYLTHIO)PHENYL)-

Systematic Name

English

Code System Code Type Description

CAS

226948-11-4

Created by admin on Sat Dec 16 08:21:41 GMT 2023 , Edited by admin on Sat Dec 16 08:21:41 GMT 2023

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PUBCHEM

9849313

Created by admin on Sat Dec 16 08:21:41 GMT 2023 , Edited by admin on Sat Dec 16 08:21:41 GMT 2023

PRIMARY

FDA UNII

3899V9A17F

Created by admin on Sat Dec 16 08:21:41 GMT 2023 , Edited by admin on Sat Dec 16 08:21:41 GMT 2023

PRIMARY

Related Record Type Details


					3899V9A17F

CRA-1000

ACTIVE MOIETY