Details
Stereochemistry | ACHIRAL |
Molecular Formula | C15H20O3 |
Molecular Weight | 248.3175 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 1 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC=C(\C=C\C(=O)OCCC(C)C)C=C1
InChI
InChIKey=UBNYRXMKIIGMKK-RMKNXTFCSA-N
InChI=1S/C15H20O3/c1-12(2)10-11-18-15(16)9-6-13-4-7-14(17-3)8-5-13/h4-9,12H,10-11H2,1-3H3/b9-6+
Molecular Formula | C15H20O3 |
Molecular Weight | 248.3175 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 1 |
Optical Activity | NONE |
Isoamyl p-Methoxycinnamate (Amiloxate) is an organic compound that absorbs ultraviolet (UV) light, which is an important cause of premature aging of the skin and in the development of melanoma and other forms of skin cancer. In Europe, Isoamyl p-Methoxycinnamate is an approved UV filter, which means the ingredient can be added to sunscreen products that are designed to protect the skin from the sun. In Europe, sunscreen products are considered cosmetic products. In the United States, sunscreen products are Over-the-Counter (OTC) drugs and only certain ingredients have been approved by the Food and Drug Administration (FDA) for use in these products. In assessing sunscreen active ingredients, the FDA reviews both safety and efficacy. The safety and efficacy of Isoamyl p-Methoxycinnamate has not yet been reviewed for sunscreen use by the FDA and it cannot be used in sunscreen drug products. For cosmetics in the United States, Isoamyl p-Methoxycinnamate can be used as a UV light absorber. In this case, the ingredient serves to protect the product from deterioration by absorbing, reflecting, or scattering UV light. It is usually combined with other ingredients in sunscreen products. But unless it is combined with ingredients that absorb UVA rays, it cannot provide enough protection on its own.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Photoallergic contact dermatitis caused by ultraviolet filters in different sunscreens. | 2008 Nov |
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Determination and validation of six sunscreen agents in suncare products by UPLC and HPLC. | 2008 Nov-Dec |
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Photoallergic contact dermatitis due to isoamyl-p-methoxycinnamate. | 2009 |
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Validation of HPLC method for the simultaneous and quantitative determination of 12 UV-filters in cosmetics. | 2010 Feb |
Patents
Substance Class |
Chemical
Created
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admin
on
Edited
Fri Dec 15 15:56:28 GMT 2023
by
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Fri Dec 15 15:56:28 GMT 2023
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376KTP06K8
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C851
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ACTIVE MOIETY |