Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C17H20N4O6S2 |
| Molecular Weight | 440.494 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C3=CC=CC(NS(C)(=O)=O)=C3)C(O)=O
InChI
InChIKey=OFKRKCHCYWQZLY-XHBSWPGZSA-N
InChI=1S/C17H20N4O6S2/c1-8-7-28-16-12(15(23)21(16)13(8)17(24)25)19-14(22)11(18)9-4-3-5-10(6-9)20-29(2,26)27/h3-6,11-12,16,20H,7,18H2,1-2H3,(H,19,22)(H,24,25)/t11-,12-,16-/m1/s1
| Molecular Formula | C17H20N4O6S2 |
| Molecular Weight | 440.494 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Cefsumide is an antibiotic of the cephalosporin group patented by Fujisawa Pharmaceutical Co. Cefsumide binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:12:24 GMT 2023
by
admin
on
Fri Dec 15 16:12:24 GMT 2023
|
| Record UNII |
3642W81J7A
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
| Name | Type | Language | ||
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Systematic Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C357
Created by
admin on Fri Dec 15 16:12:24 GMT 2023 , Edited by admin on Fri Dec 15 16:12:24 GMT 2023
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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54818-11-0
Created by
admin on Fri Dec 15 16:12:24 GMT 2023 , Edited by admin on Fri Dec 15 16:12:24 GMT 2023
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SUB07421MIG
Created by
admin on Fri Dec 15 16:12:24 GMT 2023 , Edited by admin on Fri Dec 15 16:12:24 GMT 2023
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3642W81J7A
Created by
admin on Fri Dec 15 16:12:24 GMT 2023 , Edited by admin on Fri Dec 15 16:12:24 GMT 2023
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68718
Created by
admin on Fri Dec 15 16:12:24 GMT 2023 , Edited by admin on Fri Dec 15 16:12:24 GMT 2023
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PRIMARY | |||
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C76037
Created by
admin on Fri Dec 15 16:12:24 GMT 2023 , Edited by admin on Fri Dec 15 16:12:24 GMT 2023
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Cefsumide
Created by
admin on Fri Dec 15 16:12:24 GMT 2023 , Edited by admin on Fri Dec 15 16:12:24 GMT 2023
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PRIMARY | |||
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DTXSID301023907
Created by
admin on Fri Dec 15 16:12:24 GMT 2023 , Edited by admin on Fri Dec 15 16:12:24 GMT 2023
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CHEMBL2375142
Created by
admin on Fri Dec 15 16:12:24 GMT 2023 , Edited by admin on Fri Dec 15 16:12:24 GMT 2023
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100000081812
Created by
admin on Fri Dec 15 16:12:24 GMT 2023 , Edited by admin on Fri Dec 15 16:12:24 GMT 2023
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C012135
Created by
admin on Fri Dec 15 16:12:24 GMT 2023 , Edited by admin on Fri Dec 15 16:12:24 GMT 2023
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4297
Created by
admin on Fri Dec 15 16:12:24 GMT 2023 , Edited by admin on Fri Dec 15 16:12:24 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
